Heat shock protein beta-8 Antibodies

AND HSPB8 ELISA kits, Heat shock protein beta-8 Proteins

Many biological assays use antibodies to detect Heat shock protein beta-8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Heat shock protein beta-8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Heat shock protein beta-8 antibodies...

We validate the specificity of these antibodies to Heat shock protein beta-8 by testing them on tissues known to express HSPB8 positively and negatively. Browse below to find the HSPB8 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HSPB8 Infographic by Boster Bio

All HSPB8 Products

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Anti-HSPB8/HSP22 Monoclonal Antibody

7 Q&As

Western blot analysis of 293T with HSPB8/HSP22 Mouse mAb diluted at 1:2, 000

Human, Mouse, Rat

$399
Cat # A02492-1
100μl

Anti-HSPB8/Hsp22 Antibody Picoband®

1 Q&As

Western blot analysis of HSPB8/Hsp22 using anti-HSPB8/Hsp22 antibody (A02492-2)

IHC analysis of HSPB8/Hsp22 using anti-HSPB8/Hsp22 antibody (A02492-2)

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A02492-2
100 μg/vial

Anti-HSPB8/HSP22 Rabbit Monoclonal Antibody

Western blot analysis of HSPB8/HSP22 expression in Human fetal heart lysate

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M02492
100 μl

Anti-HSPB8/Hsp22 Antibody Picoband® (monoclonal, 7D8)

Western blot analysis of HSPB8/Hsp22 using anti-HSPB8/Hsp22 antibody (M02492-2)

Flow Cytometry analysis of CACO-2 cells using anti- HSPB8/Hsp22 antibody (M02492-2)

Flow Cytometry analysis of U20S cells using anti- HSPB8/Hsp22 antibody (M02492-2)

Human, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M02492-2
100 μg/vial

Anti-HSP22 HSPB8 Antibody

Western blot analysis of Hsp22 on different lysates using anti-Hsp22 antibody at 1/1,000 dilution

ICC staining Hsp22 in Hela cells (green)

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02492
100ul

Human HSPB8 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ9UJY1
Starting from 10ug

Hsp22 (HSPB8) (NM_014365) Human Over-expression Lysate

Human

$628
Cat # LS026353
20 µg, 100 µg

HSPB8 Overview

Facts about Heat shock protein beta-8.

HSPB8 3D structure. Source: alphafold

Heat shock protein beta-8 (HSPB8)

Displays temperature-dependent chaperone activity. .

Gene Information

Human
Gene Name:	HSPB8
Uniprot:	Q9UJY1
Entrez:	26353

Family

Belongs to:

small heat shock protein (HSP20) family

Alternative Names

Alpha-crystallin C chain; CMT2L; CRYAC; DHMN2; E2IG1; E2IG1E2-induced gene 1 protein; H11; H11DHMN2; heat shock 22kDa protein 8; heat shock 27kDa protein 8; heat shock protein beta-8; HMN2; HMN2A; HSP22; HSP22CMT2L; HSPB8; Protein kinase H11; Small stress protein-like protein HSP22

Molecular Weight

Mass (kDA):
21.604 kDA

Genomic Context


Human

Location:	12q24.23
Sequence:	12; NC_000012.12 (119178931..119194746)

Tissue Specificity

Predominantly expressed in skeletal muscle and heart.

Subcellular Localizations

Cytoplasm. Nucleus. Translocates to nuclear foci during heat shock.

Diseases

Charcot-marie-tooth Disease
Peripheral Motor Neuropathy
Neoplasms
Malignant Neoplasms
Neurodegenerative Disorders
Hereditary Motor And Sensory Neuropathies
Hypertrophy
Melanoma
Neuromuscular Diseases
Sclerosis
Myopathy
Alzheimer's Disease

Primary Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Peripheral Neuropathy
Cardiac Hypertrophy
Myocardial Ischemia
Malignant Neoplasm Of Breast

Interacting Proteins

BAG3
CRYAB
DUSP12
HSPB1
HSPB2

HSPB6
HSPB7
QRICH1

Pathways

Autophagy
Cell Death
Cell Growth
Pathogenesis
Macroautophagy
Cell Proliferation
Dna Methylation
Transport
Methylation
Aging
Cell Cycle
Localization
Protein Folding

Translation
Demethylation
Programmed Cell Death
Proteolysis
Regulation Of Gene Expression
Oxidative Phosphorylation
Inflammatory Response

PTMs

Phosphorylation
Methylation
Demethylation

Cleavage
Oxidation
Ubiquitination

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSPB8

References

PMID: 11085516 by Charpentier A.H., et al. Effects of estrogen on global gene expression: identification of novel targets of estrogen action.

PMID: 11342557 by Benndorf R., et al. HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 (3DHSP27).