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- Table of Contents
Designing an IHC experiment for HIV Tat-specific factor 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HTATSF1 IHC GuideFacts about HIV Tat-specific factor 1.
In case of infection by HIV-1, it's up-regulated from the HIV-1 proteins NEF and gp120, functions as a cofactor necessary for the Tat-enhanced transcription of the virus. .
| Human | |
|---|---|
| Gene Name: | HTATSF1 |
| Uniprot: | O43719 |
| Entrez: | 27336 |

| Belongs to: |
|---|
| HTATSF1 family |

cofactor required for Tat activation of HIV-1 transcription; dJ196E23.2; HIV TAT specific factor 1; HIV Tat-specific factor 1; HIV-1 Tat specific factor 1; TAT-SF1
Mass (kDA):
85.853 kDA

| Human | |
|---|---|
| Location: | Xq26.3 |
| Sequence: | X; NC_000023.11 (136497079..136512346) |
Widely expressed.
Nucleus.




PMID: 8849451 by Zhou Q., et al. Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat.
PMID: 9649438 by Zhou Q., et al. Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages.