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- Table of Contents
Hyaluronidase-1 Antibodies
AND HYAL1 ELISA kits, Hyaluronidase-1 Proteins
Many biological assays use antibodies to detect Hyaluronidase-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hyaluronidase-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hyaluronidase-1 antibodies...
Designing a Western blot for Hyaluronidase-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HYAL1 Western Blot GuideHYAL1 Infographic by Boster Bio
All HYAL1 Products
Product
Figures
Specificity
Applications
Price
Human Hyaluronidase1/HYAL1 ELISA Kit PicoKine®
1 Citations
Human
ELISA
$750
Cat # EK1639
96 wells/kit, with removable strips.
Cat # EK1639
96 wells/kit, with removable strips.
Human, Monkey, Mouse, Rat
IHC, ICC, WB
$370
Cat # PA2181-1
100 μg/vial
Cat # PA2181-1
100 μg/vial
HYAL1 Overview
Facts about Hyaluronidase-1.
Hyaluronidase-1 (HYAL1)
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell development.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | HYAL1 |
| Uniprot: | Q12794 |
| Entrez: | 3373 |
Family
| Belongs to: |
|---|
| glycosyl hydrolase 56 family |
Alternative Names
EC 3.2.1.35; FUS2; HYAL1; HYAL-1; Hyaluronidase 1; Hyaluronoglucosaminidase 1; hyaluronoglucosaminidase-1; LUCA1; luCa-1; LUCA1hyaluronidase-1; Lung carcinoma protein 1; MGC45987; NAT6; plasma hyaluronidase; tumor suppressor LUCA-1
Molecular Weight
Mass (kDA):
48.368 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (50299889..50312951, complement) |
Tissue Specificity
Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues.
Subcellular Localizations
Secreted. Lysosome.
Diseases
- Neoplasms
- Malignant Neoplasms
- Headache
- Neoplasm Metastasis
- Carcinoma
- Tumor Angiogenesis
- Malignant Paraganglionic Neoplasm
- Tissue Adhesions
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Lung Neoplasms
- Malignant Neoplasm Of Urinary Bladder
Pathways
- Angiogenesis
- Cell Cycle
- Cell Growth
- Cell Proliferation
- Localization
- Translation
- Wound Healing
- Cell Adhesion
- Cell Migration
- Cell Cycle Arrest
- Inflammatory Response
- Cell-cell Adhesion
- Glycosylation
PTMs
- Biotinylation
- Cleavage
- Methylation
- Glycosylation
Research Areas
- Immunology
- Inflammation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HYAL1
bosterbio.com/bosterbio-gene-info-cards/HYAL1
References
PMID: 8603390 by Wei M.H., et al. Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG.
PMID: 9223416 by Frost G.I., et al. Purification, cloning, and expression of human plasma hyaluronidase.
1 Publications of Boster Hyaluronidase-1 Antibodies & ELISA Kits
- PubMed ID: 10.1111/febs.14859, Colorectal cancer‐associated ~ 6 kDa hyaluronan serves as a novel biomarker ...
*More publications can be found for each product on its corresponding product page