HIP1 Antibodies

AND HIP1 ELISA kits, HIP1 Proteins

Many biological assays use antibodies to detect HIP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HIP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HIP1 antibodies...

We validate the specificity of these antibodies to HIP1 by testing them on tissues known to express HIP1 positively and negatively. Browse below to find the HIP1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for HIP1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the HIP1 Western Blot Guide

HIP1 Infographic by Boster Bio

All HIP1 Products

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Specificity

Applications

Price

Anti-HIP1R Antibody Picoband®

Western blot analysis of HIP1R using anti-HIP1R antibody (A05059-2)

IHC analysis of HIP1R using anti-HIP1R antibody (A05059-2)

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05059-2
100 μg/vial

Anti-HIP1 Monoclonal Antibody

Western blot analysis of HIP1 using anti-HIP1 antibody (M00346-1)

Human, Mouse, Rat

IP, IF, ICC, WB

$370
Cat # M02242
100 μl

HIP1 (NM_005338) Human Over-expression Lysate

Human

$628
Cat # LS003092
20 µg, 100 µg

HIP1R (NM_003959) Human Over-expression Lysate

Human

$960
Cat # LS009026
20 µg, 100 µg

Anti-PRPF40A Antibody

Western blot (WB) analysis of PRPF40A polyclonal antibody at 1:500 dilution
Lane1:Hela whole cell lysate(40ug)
Lane2:The Brain tissue lysate of Rat(30ug)
Lane3:The Brain tissue lysate of Mouse(30ug)

Human, Mouse, Rat

$405
Cat # A06792
100ul

Anti-HIP1 Antibody Picoband®

Western blot analysis of HIP1 using anti-HIP1 antibody (A02242-1)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A02242-1
100 μg/vial

HIP1R (NM_003959) Human Recombinant Protein

Coomassie blue staining of purified HIP1R protein

$1062
Cat # PROTO75146
20 µg

HIP1 Overview

Facts about Huntingtin-interacting protein 1.

HIP1 3D structure. Source: alphafold

Huntingtin-interacting protein 1 (HIP1)

Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11532990, PubMed:11577110, PubMed:11889126). Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner (By similarity).

Regulates presynaptic nerve terminal activity (By similarity). Enhances androgen receptor (AR)-mediated transcription (PubMed:16027218).

Gene Information

Human
Gene Name:	HIP1
Uniprot:	O00291
Entrez:	3092

Family

Belongs to:

SLA2 family

Alternative Names

HIP-1; HIP-I; huntingtin interacting protein 1; huntingtin-interacting protein 1; Huntingtin-interacting protein I; ILWEQ; MGC126506

Molecular Weight

Mass (kDA):
116.221 kDA

Genomic Context


Human

Location:	7q11.23
Sequence:	7; NC_000007.14 (75533298..75738976, complement)

Tissue Specificity

Ubiquitously expressed with the highest level in brain. Expression is up-regulated in prostate and colon cancer.

Subcellular Localizations

Cytoplasm. Nucleus. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Shuttles between cytoplasm and nucleus. Nuclear translocation can be induced by AR.

Diseases

Huntington Disease
Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Leukemia
Leukemia, Myelomonocytic, Chronic
Carcinoma
Prostatic Neoplasms
Myelomonocytic Leukemia
Malignant Neoplasm Of Prostate
Neurodegenerative Disorders
Chromosomal Translocation
Myeloid Leukemia, Chronic

Mammary Neoplasms
Basal Cell Carcinoma
Williams Syndrome
Neoplasm Metastasis
Myeloid Leukemia
Metaplastic Cell Transformation
Nervousness

Interacting Proteins

Apaf1
CLTC
DAZAP2
HTT
Necap1

Pathways

Endocytosis
Clathrin-mediated Endocytosis
Transport
Localization
Pathogenesis
Cell Death
Cell Cycle
Mitosis
Cell Adhesion
Nucleosome Assembly
S Phase
Aging
Hypersensitivity

Neurogenesis
Chromosome Segregation
Platelet Aggregation
Induction Of Apoptosis
Cell Growth
Regulation Of Endocytosis
Secretion

PTMs

Phosphorylation
Cleavage
Sumoylation

Biotinylation
Acetylation
Methylation

Oxidation

Research Areas

Neurodegeneration
Neuronal Cell Markers
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HIP1

References

PMID: 11788820 by Gervais F.G., et al. Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.

PMID: 9140394 by Kalchman M.A., et al. HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain.