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- Table of Contents
Bone sialoprotein 2 Antibodies
AND IBSP ELISA kits, Bone sialoprotein 2 Proteins
Many biological assays use antibodies to detect Bone sialoprotein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bone sialoprotein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bone sialoprotein 2 antibodies...
Designing a Western blot for Bone sialoprotein 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IBSP Western Blot GuideIBSP Infographic by Boster Bio
All IBSP Products
Product
Figures
Specificity
Applications
Price
Anti-Bone Sialoprotein/IBSP Antibody Picoband®
13 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1505
100 μg/vial
Cat # PA1505
100 μg/vial
Human
$628
Cat # LS003381
20 µg, 100 µg
Cat # LS003381
20 µg, 100 µg
SDS-PAGE, Bioactivity
$281
Cat # PROTP21815-2
Starting from 10ug
Cat # PROTP21815-2
Starting from 10ug
IBSP Overview
Facts about Bone sialoprotein 2.
Bone sialoprotein 2 (IBSP)
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix.
Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
Gene Information
| Human | |
|---|---|
| Gene Name: | IBSP |
| Uniprot: | P21815 |
| Entrez: | 3381 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BNSP; Bone sialoprotein 2; Bone sialoprotein; BSP 2; BSP II; BSP; BSP2; BSPII; BSP-II; Cell binding sialoprotein; IBSP; Integrin binding sialoprotein; SP II; SPII; SP-II
Molecular Weight
Mass (kDA):
35.148 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q22.1 |
| Sequence: | 4; NC_000004.12 (87799554..87812435) |
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Malignant Neoplasms
- Neoplasm Metastasis
- Tissue Adhesions
- Malignant Neoplasm Of Breast
- Bone Neoplasms
- Metastatic Malignant Neoplasm To The Bone
- Mammary Neoplasms
- Osteosarcoma
- Carcinoma
- Hypertrophy
- Osteoporosis
Pathways
- Osteoblast Differentiation
- Regeneration
- Cell Proliferation
- Cell Differentiation
- Localization
- Bone Resorption
- Cell Adhesion
- Bone Development
- Dentinogenesis
- Bone Remodeling
- Secretion
- Root Development
- Pathogenesis
PTMs
- Phosphorylation
- Cleavage
- Sulphation
- Glycosylation
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IBSP
bosterbio.com/bosterbio-gene-info-cards/IBSP
References
PMID: 2404984 by Fisher L.W., et al. Human bone sialoprotein. Deduced protein sequence and chromosomal localization.
PMID: 8406493 by Kerr J.M., et al. The human bone sialoprotein gene (IBSP): genomic localization and characterization.
3 Publications of Boster Bone sialoprotein 2 Antibodies & ELISA Kits
- PubMed ID: 30988819, Liu B,Xu M,Guo Z,Liu J,Chu X,Jiang H.Interleukin-8 promotes prostate cancer bone...
- PubMed ID: 27347083, Effect of kidney-reinforcing and marrow-beneficial Chinese medicine on bone meta...
- PubMed ID: 24265840, The Osteogenic Potential of Mesoporous Bioglasses/Silk and Non-Mesoporous Biogla...
*More publications can be found for each product on its corresponding product page