IDH3A Antibodies

AND IDH3A ELISA kits, IDH3A Proteins

Many biological assays use antibodies to detect IDH3A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IDH3A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IDH3A antibodies...

We validate the specificity of these antibodies to IDH3A by testing them on tissues known to express IDH3A positively and negatively. Browse below to find the IDH3A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for IDH3A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the IDH3A IHC Guide

IDH3A Infographic by Boster Bio

All IDH3A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-IDH3A Antibody Picoband®

Western blot analysis of ILDR1 using anti-ILDR1 antibody (A09544-3)

IHC analysis of ILDR1 using anti-ILDR1 antibody (A09544-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A09544-3
100 µg/vial

IDH3A (NM_005530) Human Over-expression Lysate

Human

$628
Cat # LS003419
20 µg, 100 µg

IDH3A Overview

Facts about Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial.

IDH3A 3D structure. Source: alphafold

Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A)

Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full action of the heterotetramer (containing two subunits of IDH3A, among IDH3B and among IDH3G) requires the assembly and cooperative function of both heterodimers.

Gene Information

Human
Gene Name:	IDH3A
Uniprot:	P50213
Entrez:	3419

Family

Belongs to:

isocitrate and isopropylmalate dehydrogenases family

Alternative Names

EC 1.1.1; EC 1.1.1.41; H-IDH alpha; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; isocitrate dehydrogenase 3 (NAD+) alpha; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit; NAD+-specific ICDH

Molecular Weight

Mass (kDA):
39.592 kDA

Genomic Context


Human

Location:	15q25.1
Sequence:	15; NC_000015.10 (78149362..78171945)

Subcellular Localizations

Mitochondrion.

Diseases

Disease Of Adrenal Medulla
Malignant Neoplasm Of Breast
Neurodegenerative Disorders
Lung Diseases
Kidney Failure
Parkinson Disease
Chronic Obstructive Airway Disease
Lung Diseases, Obstructive
Cataract
Severe Sepsis

Systemic Infection
Malignant Neoplasms
Inflammation
Lymphocytic Choriomeningitis

Pathways

Oxidative Phosphorylation
Transport
Aging
Fatty Acid Oxidation
Glycolysis
Secretion

PTMs

Phosphorylation

Decarboxylation

Oxidation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IDH3A

References

PMID: 7755589 by Kim Y.O., et al. Characterization of a cDNA clone for human NAD(+)-specific isocitrate dehydrogenase alpha-subunit and structural comparison with its isoenzymes from different species.

PMID: 28139779 by Ma T., et al. The beta and gamma subunits play distinct functional roles in the alpha2betagamma heterotetramer of human NAD-dependent isocitrate dehydrogenase.