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- Table of Contents
Facts about Immunoglobulin superfamily member 6.
| Human | |
|---|---|
| Gene Name: | IGSF6 |
| Uniprot: | O95976 |
| Entrez: | 10261 |

| Belongs to: |
|---|
| No superfamily |

DORA; DORAdown-regulated by activation (immunoglobulin superfamily); IGSF6; immunoglobulin superfamily member 6; immunoglobulin superfamily, member 6; Protein DORA
Mass (kDA):
27.013 kDA

| Human | |
|---|---|
| Location: | 16p12.2 |
| Sequence: | 16; NC_000016.10 (21639550..21652608, complement) |
Expressed in peripheral blood lymphocytes, spleen and lymph node, with low levels in thymus, bone marrow and fetal liver. No expression in non-immune tissues.
Membrane; Single-pass type I membrane protein.




PMID: 9809579 by Bates E.E.M., et al. CD40L activation of dendritic cells down-regulates DORA, a novel member of the immunoglobulin superfamily.
PMID: 11132146 by Bates E.E.M., et al. The mouse and human IGSF6 (DORA) genes map to the inflammatory bowel disease 1 locus and are embedded in an intron of a gene of unknown function.