IKZF5 Antibodies

AND IKZF5 ELISA kits, IKZF5 Proteins

Many biological assays use antibodies to detect IKZF5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IKZF5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IKZF5 antibodies...

We validate the specificity of these antibodies to IKZF5 by testing them on tissues known to express IKZF5 positively and negatively. Browse below to find the IKZF5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IKZF5 Infographic by Boster Bio

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IKZF5 Overview

Facts about Zinc finger protein Pegasus.

IKZF5 3D structure. Source: alphafold

Zinc finger protein Pegasus (IKZF5)

DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor.

Gene Information

Human
Gene Name:	IKZF5
Uniprot:	Q9H5V7
Entrez:	64376

Family

Belongs to:

Ikaros C2H2-type zinc-finger protein family

Alternative Names

DKFZp781B0249; FLJ22973; IKAROS family zinc finger 5 (Pegasus); Ikaros family zinc finger protein 5; PEGASUS; zinc finger protein Pegasus; zinc finger protein, subfamily 1A, 5 (Pegasus); zinc finger protein, subfamily 1A, 5; zinc finger transcription factor Pegasus; ZNFN1A5

Molecular Weight

Mass (kDA):
46.51 kDA

Genomic Context


Human

Location:	10q26.13
Sequence:	10; NC_000010.11 (122990806..123008826, complement)

Tissue Specificity

Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT- 4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.

Subcellular Localizations

Nucleus.

Diseases

Cholangiocarcinoma
Hypertensive Disease
Essential Hypertension
Hyperlipidemia
Diabetes Mellitus
Dysequilibrium Syndrome

Interacting Proteins

IKZF3

PTMs

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IKZF5

References

PMID: 10978333 by Perdomo J., et al. Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.