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- Table of Contents
INSRR Antibodies
AND INSRR ELISA kits, INSRR Proteins
Many biological assays use antibodies to detect INSRR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INSRR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INSRR antibodies...
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INSRR Infographic by Boster Bio
All INSRR Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # M08212
100 μl
Cat # M08212
100 μl
Human
$960
Cat # LS003645
20 µg, 100 µg
Cat # LS003645
20 µg, 100 µg
INSRR Overview
Facts about Insulin receptor-related protein.
Insulin receptor-related protein (INSRR)
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor that's activated by increased extracellular pH.
Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. .
Gene Information
| Human | |
|---|---|
| Gene Name: | INSRR |
| Uniprot: | P14616 |
| Entrez: | 3645 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
EC 2.7.10; EC 2.7.10.1; INSRR; insulin receptor-related protein; insulin receptor-related receptor; IRR; IRRIR-related receptor
Molecular Weight
Mass (kDA):
143.72 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q23.1 |
| Sequence: | 1; NC_000001.11 (156840063..156859117, complement) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Diabetes Mellitus, Non-insulin-dependent
- Diabetes Mellitus
- Insulin Resistance
- Malignant Neoplasms
- Dysequilibrium Syndrome
- Salivary Gland Neoplasms
- Metabolic Alkalosis
- Insulinoma
- Malignant Paraganglionic Neoplasm
- Carcinoma
- Neoplasms
- Adenoid Cystic Carcinoma
Pathways
- Methylation
- Insulin Secretion
- Dna Methylation
- Cell Growth
- Localization
- Glycolysis
PTMs
- Phosphorylation
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INSRR
bosterbio.com/bosterbio-gene-info-cards/INSRR
References
PMID: 10226785 by Haenze J., et al. Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor.
PMID: 2768234 by Shier P., et al. Primary structure of a putative receptor for a ligand of the insulin family.