INTS12 Antibodies

AND INTS12 ELISA kits, INTS12 Proteins

Many biological assays use antibodies to detect INTS12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INTS12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INTS12 antibodies...

We validate the specificity of these antibodies to INTS12 by testing them on tissues known to express INTS12 positively and negatively. Browse below to find the INTS12 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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INTS12 Infographic by Boster Bio

All INTS12 Products

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Specificity

Applications

Price

PHF22 (INTS12) (NM_020395) Human Over-expression Lysate

PHF22 (INTS12) Human Over-expression Lysates NM_001142471

Human

$628
Cat # LS057117
20 µg, 100 µg

Anti-INTS12 Antibody Picoband®

Western blot analysis of INTS12 using anti-INTS12 antibody (A11402-1)

Flow Cytometry analysis of MCF-7 cells using anti-INTS12 antibody (A11402-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A11402-1
100 µg/vial

Anti-Zebrafish INTS12 Antibody Picoband®

Western blot analysis of INTS12 using anti-INTS12 antibody (AZQ6IQU7)

IHC analysis of INTS12 using anti-INTS12 antibody (AZQ6IQU7)

Zebrafish

IF, IHC, WB

$470
Cat # AZQ6IQU7
100 μg/vial

INTS12 Overview

Facts about Integrator complex subunit 12.

INTS12 3D structure. Source: alphafold

Integrator complex subunit 12 (INTS12)

Part of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is linked to the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (PubMed:16239144).

Mediates recruitment of cytoplasmic dynein to the nuclear envelope, likely as part of the INT complicated (PubMed:23904267). .

Gene Information

Human
Gene Name:	INTS12
Uniprot:	Q96CB8
Entrez:	57117

Family

Belongs to:

Integrator subunit 12 family

Alternative Names

Int12; integrator complex subunit 12; PHD finger protein 22INT12; PHF22; SBBI22

Molecular Weight

Mass (kDA):
48.808 kDA

Genomic Context


Human

Location:	4q24
Sequence:	4; NC_000004.12 (105682627..105708725, complement)

Subcellular Localizations

Nucleus.

Diseases

Lung Diseases, Obstructive
Chronic Obstructive Airway Disease
Lung Diseases

Interacting Proteins

GTF2IRD1

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INTS12

References

PMID: 16239144 by Baillat D., et al. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

PMID: 23904267 by Jodoin J.N., et al. Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.