Integrin alpha-1 Antibodies

AND ITGA1 ELISA kits, Integrin alpha-1 Proteins

Many biological assays use antibodies to detect Integrin alpha-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-1 antibodies...

We validate the specificity of these antibodies to Integrin alpha-1 by testing them on tissues known to express ITGA1 positively and negatively. Browse below to find the ITGA1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ITGA1 Infographic by Boster Bio

All ITGA1 Products

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Specificity

Applications

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Anti-Integrin alpha 1/ITGA1 Antibody Picoband®

2 Citations 5 Q&As

Western blot analysis of Integrin Alpha 1/ITGA1 using anti-Integrin Alpha 1/ITGA1 antibody (PA1045-1)

IHC analysis of Integrin Alpha 1/ITGA1 using anti-Integrin Alpha 1/ITGA1 antibody (PA1045-1)

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1045-1
100 μg/vial

Integrin alpha 1 (ITGA1) (NM_181501) Human Over-expression Lysate

Human

$960
Cat # LS003672
20 µg, 100 µg

Human CD49A ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2225
96 wells/kit, with removable strips.

ITGA1 Overview

Facts about Integrin alpha-1.

ITGA1 3D structure. Source: alphafold

Integrin alpha-1 (ITGA1)

Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It admits the proline-hydroxylated sequence G-F-P-G- E-R in collagen.

Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. .

Gene Information

Human
Gene Name:	ITGA1
Uniprot:	P56199
Entrez:	3672

Family

Belongs to:

integrin alpha chain family

Alternative Names

CD49 antigen-like family member A; CD49a antigen; CD49a; Integrin alpha 1; integrin, alpha 1; ITGA1; Laminin and collagen receptor; very late activation protein 1; VLA-1; VLA1integrin alpha-1

Molecular Weight

Mass (kDA):
130.848 kDA

Genomic Context


Human

Location:	5q11.2
Sequence:	5; NC_000005.10 (52787916..52959209)

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Fracture
Osteoporosis
Dysequilibrium Syndrome
Malignant Neoplasms
Neoplasms
Liver Diseases
Mutation Abnormality
Neoplasm Metastasis
Intracranial Arteriovenous Malformation
Malnutrition
Tic, Vocal
Hereditary Hemorrhagic Telangiectasia
Colonic Neoplasms

Malignant Tumor Of Colon
Behavioral Tic
Arteriovenous Malformation
Carcinoma
Insulin Resistance
Fibrosis
Tumor Angiogenesis

Pathways

Cell Proliferation
Cell Cycle
Stem Cell Proliferation
Mesenchymal Stem Cell Proliferation
Transport
Regulation Of Cell Cycle
Osteoblast Differentiation
Insulin Secretion
Megakaryocyte Differentiation
Methylation

Drug Resistance
Cell Motility
Angiogenesis
Secretion

PTMs

Demethylation

Methylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGA1

References

PMID: 8428973 by Briesewitz R., et al. Expression of native and truncated forms of the human integrin alpha 1 subunit.

PMID: 15592458 by Mattila E., et al. Negative regulation of EGFR signalling through integrin-alpha1beta1- mediated activation of protein tyrosine phosphatase TCPTP.

1 Publications of Boster Integrin alpha-1 Antibodies & ELISA Kits

PubMed ID: 24643246, A Small Physiological Electric Field Mediated Responses of Extravillous Trophobl...

*More publications can be found for each product on its corresponding product page