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- Table of Contents
Integrin alpha-1 Antibodies
AND ITGA1 ELISA kits, Integrin alpha-1 Proteins
Many biological assays use antibodies to detect Integrin alpha-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-1 antibodies...
Designing a Western blot for Integrin alpha-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ITGA1 Western Blot GuideITGA1 Infographic by Boster Bio
All ITGA1 Products
Product
Figures
Specificity
Applications
Price
Anti-Integrin alpha 1/ITGA1 Antibody Picoband®
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1045-1
100 μg/vial
Cat # PA1045-1
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M07820-1
100 μg
Cat # M07820-1
100 μg
Human
$960
Cat # LS003672
20 µg, 100 µg
Cat # LS003672
20 µg, 100 µg
ITGA1 Overview
Facts about Integrin alpha-1.
Integrin alpha-1 (ITGA1)
Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It admits the proline-hydroxylated sequence G-F-P-G- E-R in collagen.
Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGA1 |
| Uniprot: | P56199 |
| Entrez: | 3672 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
CD49 antigen-like family member A; CD49a antigen; CD49a; Integrin alpha 1; integrin, alpha 1; ITGA1; Laminin and collagen receptor; very late activation protein 1; VLA-1; VLA1integrin alpha-1
Molecular Weight
Mass (kDA):
130.848 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q11.2 |
| Sequence: | 5; NC_000005.10 (52787916..52959209) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Fracture
- Osteoporosis
- Dysequilibrium Syndrome
- Malignant Neoplasms
- Neoplasms
- Liver Diseases
- Mutation Abnormality
- Neoplasm Metastasis
- Intracranial Arteriovenous Malformation
- Malnutrition
- Tic, Vocal
- Hereditary Hemorrhagic Telangiectasia
- Colonic Neoplasms
Pathways
- Cell Proliferation
- Cell Cycle
- Stem Cell Proliferation
- Mesenchymal Stem Cell Proliferation
- Transport
- Regulation Of Cell Cycle
- Osteoblast Differentiation
- Insulin Secretion
- Megakaryocyte Differentiation
- Methylation
PTMs
- Demethylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGA1
bosterbio.com/bosterbio-gene-info-cards/ITGA1
References
PMID: 8428973 by Briesewitz R., et al. Expression of native and truncated forms of the human integrin alpha 1 subunit.
PMID: 15592458 by Mattila E., et al. Negative regulation of EGFR signalling through integrin-alpha1beta1- mediated activation of protein tyrosine phosphatase TCPTP.
1 Publications of Boster Integrin alpha-1 Antibodies & ELISA Kits
- PubMed ID: 24643246, A Small Physiological Electric Field Mediated Responses of Extravillous Trophobl...
*More publications can be found for each product on its corresponding product page