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- Table of Contents
1 Q&As
Facts about Inositol-trisphosphate 3-kinase C.
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Human | |
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Gene Name: | ITPKC |
Uniprot: | Q96DU7 |
Entrez: | 80271 |
Belongs to: |
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inositol phosphokinase (IPK) family |
inositol 14,5-trisphosphate 3-kinase CIP3K C; inositol-trisphosphate 3-kinase C; InsP 3 kinase C; InsP 3-kinase C; IP3 3-kinase C; IP3-3KC; IP3KCEC 2.7.1.127
Mass (kDA):
75.207 kDA
Human | |
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Location: | 19q13.2 |
Sequence: | 19; NC_000019.10 (40717112..40740860) |
Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.
Nucleus. Cytoplasm. Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.
PMID: 11085927 by Dewaste V., et al. Cloning and expression of a cDNA encoding human inositol 1,4,5- trisphosphate 3-kinase C.
PMID: 12747803 by Dewaste V., et al. The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells.