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- Table of Contents
IL12B Antibodies
AND IL12B ELISA kits, IL12B Proteins
Many biological assays use antibodies to detect IL12B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IL12B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IL12B antibodies...
Designing a Western blot for IL12B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IL12B Western Blot GuideIL12B Infographic by Boster Bio
All IL12B Products
Product
Figures
Specificity
Applications
Price
Mouse IL-12(p40) ELISA Kit PicoKine®
52 Citations
Mouse
ELISA
$499
Cat # EK0932
96 wells/kit, with removable strips.
Cat # EK0932
96 wells/kit, with removable strips.
Porcine
ELISA
$499
Cat # EK2353
96 wells/kit, with removable strips.
Cat # EK2353
96 wells/kit, with removable strips.
Canine
ELISA
$499
Cat # EK2340
96 wells/kit, with removable strips.
Cat # EK2340
96 wells/kit, with removable strips.
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M01152-3
100 µl/vial
Cat # M01152-3
100 µl/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01152-4
100 μg
Cat # M01152-4
100 μg
Human
ELISA
$369
Cat # EK0423
96wells/kit, with removable strips.
Cat # EK0423
96wells/kit, with removable strips.
Mouse
Cell Culture
$77
Cat # PROTP43432-1
5ug,20ug,100ug
Cat # PROTP43432-1
5ug,20ug,100ug
Human
Cell Culture
$77
Cat # PROTP29460-6
5ug,20ug,100ug
Cat # PROTP29460-6
5ug,20ug,100ug
IL12B Overview
Facts about Interleukin-12 subunit beta.
Interleukin-12 subunit beta (IL12B)
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. .
Gene Information
| Human | |
|---|---|
| Gene Name: | IL12B |
| Uniprot: | P29460 |
| Entrez: | 3593 |
Family
| Belongs to: |
|---|
| IL-12B family |
Alternative Names
CLMF p40; CLMF; CLMF2; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL12 p40; IL-12 p40; IL-12 subunit p40; IL12B; IL-12B; IL-12BNK cell stimulatory factor chain 2; interleukin 12, p40; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocytematuration factor 2, p40); interleukin-12 beta chain; interleukin-12 subunit beta; natural killer cell stimulatory factor, 40 kD subunit; NKSF; NKSF2; NKSF2IL12, subunit p40
Molecular Weight
Mass (kDA):
37.169 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q33.3 |
| Sequence: | 5; NC_000005.10 (159314780..159330487, complement) |
Subcellular Localizations
Secreted.
Diseases
- Psoriasis
- Crohn Disease
- Autoimmune Reaction
- Inflammation
- Autoimmune Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Insulin-dependent
- Tuberculosis
- Infective Disorder
- Inflammatory Bowel Diseases
- Arthritis
- Mycobacterium Infections
- Colitis
Interacting Proteins
- IL12A
- IL23A
- Il23a
Pathways
- Pathogenesis
- Immune Response
- Secretion
- Cytokine Production
- Autophagy
- Localization
- Macrophage Activation
- Inflammatory Response
- Innate Immune Response
- Cell Differentiation
- Cell Activation
- Complement Activation
- Adaptive Immune Response
PTMs
- Phosphorylation
- Cleavage
- Acetylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL12B
bosterbio.com/bosterbio-gene-info-cards/IL12B
References
PMID: 1674604 by Gubler U., et al. Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor.
PMID: 1673147 by Wolf S.F., et al. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells.
41 Publications of Boster IL12B Antibodies & ELISA Kits
- PubMed ID: 10.3892/mmr.2019.10694, Role of CCR7 on dendritic cell‑mediated immune tolerance in the airways of all...
- PubMed ID: 10.3892/etm.2018.6846, Atorvastatin reverses the dysfunction of human umbilical vein endothelial cells ...
- PubMed ID: 10.1111/j.1582-4934.2009.00806.x, Anti‐arthritis activity of cationic materials
- PubMed ID: 10.1080/08820139.2016.1248561, Vinpocetine Inhibited the CpG Oligodeoxynucleotide-induced Immune Response in Pl...
- PubMed ID: 10.1021/acsami.0c01413, Hydrogen Peroxide-Activatable Nanoparticles for Luminescence Imaging and In Situ...
- PubMed ID: 10.1016/j.micinf.2012.10.008, Extraordinary GU-rich single-strand RNA identified from SARS coronavirus contrib...
- PubMed ID: 10.1016/j.jff.2019.03.001, Quercetin confers protection of murine sepsis by inducing macrophage M2 polariza...
- PubMed ID: 10.1016/j.jep.2017.12.009, Pathway analysis of global gene expression change in dendritic cells induced by ...
- PubMed ID: 10.1016/j.ijbiomac.2021.10.135, An antigen display system of GEM nanoparticles based on affinity peptide ligands
- PubMed ID: 10.1016/j.ijbiomac.2021.03.006, Structural characteristics and immunopotentiation activity of two polysaccharide...
- PubMed ID: 10.1016/j.foodhyd.2018.11.018, Polysaccharide from natural Cordyceps sinensis ameliorated intestinal injury and...
- PubMed ID: 10.1016/j.actbio.2021.07.063, Sialic acid conjugate-modified liposomes enable tumor homing of epirubicin via n...
- PubMed ID: 10.1007/s13770-021-00405-5, The Therapeutic Effects of Exosomes Derived from Human Umbilical Cord Mesenchyma...
- PubMed ID: 10.1007/s10529-017-2342-1, Novel adjuvant for immunization against tuberculosis: DNA vaccine expressing Myc...
- PubMed ID: 10.1002/adhm.201500930, Genetically Engineered Virus Nanofibers as an Efficient Vaccine for Preventing F...
- PubMed ID: 10.1002/adhm.201500930, Genetically Engineered Virus Nanofibers as an Efficient Vaccine for Preventing F...
- PubMed ID: 10.1002/adhm.201500930, Genetically Engineered Virus Nanofibers as an Efficient Vaccine for Preventing F...
- PubMed ID: , VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondr...
- PubMed ID: , GSH depletion liposome adjuvant for augmenting the photothermal immunotherapy of...
- PubMed ID: 33676979, He Y, Peng H, Zhang H, Liu Y, Sun H. Structural characteristics and immunopotent...
- PubMed ID: 26582004, Association of CTLA4 exon-1 polymorphism with the tumor necrosis factor-α in th...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page