Jmy Antibodies

AND Jmy ELISA kits, Jmy Proteins

Many biological assays use antibodies to detect Jmy, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Jmy in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Jmy antibodies...

We validate the specificity of these antibodies to Jmy by testing them on tissues known to express Jmy positively and negatively. Browse below to find the Jmy antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Jmy? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the JMY IHC Guide

Jmy Infographic by Boster Bio

All Jmy Products

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Product

Figures

Specificity

Applications

Price

Anti-JMY Antibody

Western Blot analysis of various cells using JMY Polyclonal Antibody

Western blot analysis of lysates from COLO cells, using JMY Antibody

Immunohistochemical analysis of paraffin-embedded human liver cancer

Human, Mouse

ELISA, IHC, WB

$380
Cat # A05423
100ul

JMY Colorimetric Cell-Based ELISA

Western blot analysis of extracts from COLO cells

Human, Mouse

ELISA

$480
Cat # EKC1614
1 kit, containing one 96-well plate and all necessary reagents

JMY (NM_152405) Human Over-expression Lysate

Human

$960
Cat # LS133746
20 µg, 100 µg

JMY (NM_152405) Human Recombinant Protein

Coomassie blue staining of purified JMY protein

$1249
Cat # PROTQ8N9B5
20 µg

Jmy Overview

Facts about Junction-mediating and -regulatory protein.

Junction-mediating and -regulatory protein (Jmy)

Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, functions as a cofactor that raises p53/TP53 response via its interaction with p300/EP300.

Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response like DNA damage. In cytoplasm, functions as a nucleation-promoting factor for both branched and unbranched actin filaments.

Gene Information

Mouse
Gene Name:	Jmy
Uniprot:	Q9QXM1
Entrez:	57748

Family

Belongs to:

JMY family

Alternative Names

FLJ37870; junction mediating and regulatory protein, p53 cofactor; junction-mediating and regulatory protein; junction-mediating and -regulatory protein; MGC163496; WAS protein homology region 2 domain containing 1-like 3; WHDC1L3

Molecular Weight

Mass (kDA):
110.586 kDA

Genomic Context


Mouse

Location:	13\|13 C3
Sequence:	13;

Tissue Specificity

Widely expressed, except in testis where it is expressed at low level.

Diseases

Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasms
Cell Invasion
Tissue Adhesions
Ataxia
Hypoxia
Ataxia Telangiectasia
Telangiectasis
Inflammation
Wiskott-aldrich Syndrome
Leukoencephalopathy, Progressive Multifocal
Metaplasia

Malignant Neoplasm Of Breast
Gastrointestinal Neoplasms
Pediatric Obesity
Neoplasm Invasiveness
Carcinoma
Dysplasia
Chromosome Breakage

Pathways

Actin Nucleation
Cell Cycle
Cell Migration
Cell Cycle Arrest
Cell Motility
Endocytosis
Localization
Transport
Cell Adhesion
Aging
Meiosis
Cell Proliferation
Cell Death

Clathrin-mediated Endocytosis
Spermatogenesis
Nuclear Transport
Phagocytosis
Translation
Nuclear Import
Response To Stress

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Jmy

References

PMID: 10518217 by Shikama N., et al. A novel cofactor for p300 that regulates the p53 response.

PMID: 11511361 by Demonacos C., et al. A TPR motif cofactor contributes to p300 activity in the p53 response.