KCNMB2 Antibodies

AND KCNMB2 ELISA kits, KCNMB2 Proteins

Many biological assays use antibodies to detect KCNMB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNMB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNMB2 antibodies...

We validate the specificity of these antibodies to KCNMB2 by testing them on tissues known to express KCNMB2 positively and negatively. Browse below to find the KCNMB2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNMB2 Infographic by Boster Bio

All KCNMB2 Products

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Anti-KCNMB2 Antibody

4 Q&As

Western Blot analysis of various cells using MaxiKβ2 Polyclonal Antibody diluted at 1:500

Western blot analysis of the lysates from HepG2 cells using KCNMB2 antibody

Western blot analysis of lysates from Jurkat, COLO, and HepG2 cells, using KCNMB2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A30582
100ul

Anti-MaxiK Beta 2 (I186) KCNMB2 Antibody

Western blot (WB) analysis of MaxiKβ2 (I186) pAb at 1:500 dilution
Lane1:SK-OVCAR3 whole cell lysate(40ug)
Lane2:A2780 whole cell lysate(40ug)
Lane3:The Ovary tissue lysate of Rat(40ug)
Lane4:The Brain tissue lysate of Mouse(40ug)

Immunohistochemistry (IHC) analyzes of MaxiKβ2 (I186) pAb in paraffin-embedded human breast carcinoma tissue at 1:50

Human, Mouse, Rat

IHC, WB

$405
Cat # A08181-1
100ul

Anti-KCNMB2 Antibody (N-term)

Human, Mouse, Rat

$299
Cat # M08181
80 µl

KCNMB2 (NM_181361) Human Over-expression Lysate

KCNMB2 Human Over-expression Lysates NM_005832

Human

$628
Cat # LS010242
20 µg, 100 µg

KCNMB2 Overview

Facts about Calcium-activated potassium channel subunit beta-2.

KCNMB2 3D structure. Source: alphafold

Calcium-activated potassium channel subunit beta-2 (KCNMB2)

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.

Gene Information

Human
Gene Name:	KCNMB2
Uniprot:	Q9Y691
Entrez:	10242

Family

Belongs to:

KCNMB (TC 8.A.14.1) family

Alternative Names

BK channel subunit beta-2; BKbeta2; calcium-activated potassium channel subunit beta-2; Calcium-activated potassium channel, subfamily M subunit beta-2; Charybdotoxin receptor subunit beta-2; hbeta2; hbeta3; k(VCA)beta-2; large conductance calcium-activated potassium channel beta 2 subunit; large-conductance Ca2+-activated K+ channel beta2 subunit; Maxi K channel subunit beta-2; MaxiK channel beta 2 subunit; MGC22431; potassium large conductance calcium-activated channel, subfamily M, beta member2; slo-beta-2

Molecular Weight

Mass (kDA):
27.13 kDA

Genomic Context


Human

Location:	3q26.32
Sequence:	3; NC_000003.12 (178536394..178844429)

Tissue Specificity

Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Epilepsy
Hypoxia
Febrile Convulsions
Anoxia

Pathways

Cell Death
Osteoblast Proliferation

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNMB2

References

PMID: 10097176 by Wallner M., et al. Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homolog.

PMID: 10692449 by Brenner R., et al. Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.