KDM7A Antibodies

AND KDM7A ELISA kits, KDM7A Proteins

Many biological assays use antibodies to detect KDM7A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KDM7A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KDM7A antibodies...

We validate the specificity of these antibodies to KDM7A by testing them on tissues known to express KDM7A positively and negatively. Browse below to find the KDM7A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KDM7A Infographic by Boster Bio

All KDM7A Products

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Anti-Lysine-specific demethylase 7A KDM7A Antibody

Western blot analysis of extracts of various cell lines, using KDM7A antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A09346
100ul

JHDM1D (KDM7A) (NM_030647) Human Over-expression Lysate

Human

$960
Cat # LS080853
20 µg, 100 µg

KDM7A Overview

Facts about Lysine-specific demethylase 7A.

KDM7A 3D structure. Source: alphafold

Lysine-specific demethylase 7A (KDM7A)

Histone demethylase needed for brain development. Specifically demethylates dimethylated'Lys-9' and'Lys-27' (H3K9me2 and H3K27me2( respectively) of histone H3 and monomethylated histone H4'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code.

Specifically binds trimethylated'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it doesn't have any demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3.

Gene Information

Human
Gene Name:	KDM7A
Uniprot:	Q6ZMT4
Entrez:	80853

Family

Belongs to:

JHDM1 histone demethylase family

Alternative Names

Lysine-specific demethylase 7A

Molecular Weight

Mass (kDA):
106.557 kDA

Genomic Context


Human

Location:	7q34
Sequence:	7; NC_000007.14 (140084746..140176983, complement)

Subcellular Localizations

Nucleus.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KDM7A

References

PMID: 20194436 by Tsukada Y., et al. KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.

PMID: 20622853 by Qi H.H., et al. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development.