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Setd7 Antibodies
AND Setd7 ELISA kits, Setd7 Proteins
Many biological assays use antibodies to detect Setd7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Setd7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Setd7 antibodies...
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Setd7 Infographic by Boster Bio
All Setd7 Products
Product
Figures
Specificity
Applications
Price
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M02793-1
100 µl
Cat # M02793-1
100 µl
Setd7 Overview
Facts about Histone-lysine N-methyltransferase SETD7.
Histone-lysine N-methyltransferase SETD7 (Setd7)
Histone methyltransferase that especially monomethylates'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Setd7 |
| Uniprot: | Q8VHL1 |
| Entrez: | 73251 |
Family
| Belongs to: |
|---|
| class V-like SAM-binding methyltransferase superfamily |
Alternative Names
EC 2.1.1.43; H3-K4-HMTase SETD7; histone H3-lysine 4-specific methyltransferase; histone-lysine N-methyltransferase SETD7; KIAA1717SET domain-containing protein 7; KMT7FLJ21193; Lysine N-methyltransferase 7; SET domain containing (lysine methyltransferase) 7; SET7/9Histone H3-K4 methyltransferase SETD7; SET7Set9; SET9
Molecular Weight
Mass (kDA):
40.506 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 3|3 C |
| Sequence: | 3; |
Diseases
- Neoplasms
- Malignant Neoplasms
- Diabetes Mellitus
- Hyperglycemia
- Diabetic Angiopathies
- Inflammation
- Genotoxic Stress
- Leukemia
- Complications Of Diabetes Mellitus
- Carcinogenesis
- Autoimmune Reaction
- Oncogene Activation Process
- Diabetic Nephropathy
Pathways
- Methylation
- Cell Cycle
- Histone Methylation
- Chromatin Remodeling
- Histone Modification
- Localization
- Demethylation
- Cell Death
- Gene Silencing
- Histone Acetylation
- Mitosis
- Dna Methylation
- Pathogenesis
PTMs
- Methylation
- Acetylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Setd7
bosterbio.com/bosterbio-gene-info-cards/Setd7
References
PMID: 11779497 by Wang H., et al. Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.
PMID: 12711597 by Chakrabarti S.K., et al. Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells.