GTPase KRas Antibodies

AND KRAS ELISA kits, GTPase KRas Proteins

Many biological assays use antibodies to detect GTPase KRas, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GTPase KRas in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GTPase KRas antibodies...

We validate the specificity of these antibodies to GTPase KRas by testing them on tissues known to express KRAS positively and negatively. Browse below to find the KRAS antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for GTPase KRas? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the KRAS Western Blot Guide

KRAS Infographic by Boster Bio

All KRAS Products

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Product

Figures

Specificity

Applications

Price

Anti-KRAS+HRAS+NRAS Rabbit Monoclonal Antibody

6 Citations

Immunofluorescent analysis of Hela cells, using KRAS+HRAS+NRAS Antibody

KRAS+HRAS+NRAS was immunoprecipitated from 1mg of A549 whole cell lysate

Western blot analysis of KRAS+HRAS+NRAS using anti-KRAS+HRAS+NRAS antibody (M00099-1)

Human, Mouse, Rat

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M00099-1
100 μl

KRAS (NM_033360) Human Over-expression Lysate

KRAS Human Over-expression Lysates NM_004985

Human

$628
Cat # LS003845
20 µg, 100 µg

Anti-KRAS Antibody Picoband®

Western blot analysis of KRAS using anti-KRAS antibody (A00046-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A00046-2
100 μg/vial

Human K-RAS Recombinant Protein

SDS-PAGE

$243
Cat # PROTP01116
Starting from 20ug

KRAS Overview

Facts about GTPase KRas.

KRAS 3D structure. Source: alphafold

GTPase KRas (KRAS)

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an essential role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838).

Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells at a ZNF304-dependent manner (PubMed:24623306). .

Gene Information

Human
Gene Name:	KRAS
Uniprot:	P01116
Entrez:	3845

Family

Belongs to:

small GTPase superfamily

Alternative Names

cellular c-Ki-ras2 proto-oncogene; c-Ki-ras; C-K-RAS; GTPase KRas; KI-RAS; Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog; K-Ras 2; K-ras p21 protein; KRAS1; K-RAS2A; K-RAS2B; KRAS2NS3; K-RAS4A; K-RAS4B; NS; oncogene KRAS2; PR310 c-K-ras oncogene; RASK2c-Kirsten-ras protein; transforming protein p21; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Molecular Weight

Mass (kDA):
21.656 kDA

Genomic Context


Human

Location:	12p12.1
Sequence:	12; NC_000012.12 (25205246..25250929, complement)

Subcellular Localizations

Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol.

Diseases

Malignant Neoplasms
Neoplasms
Colorectal Cancer
Colorectal Neoplasms
Adenocarcinoma
Carcinoma
Lung Neoplasms
Malignant Neoplasm Of Lung
Neoplasm Metastasis
Non-small Cell Lung Carcinoma
Colorectal Cancer Metastatic
Cell Transformation, Neoplastic
Microsatellite Instability

Pancreatic Neoplasm
Malignant Tumor Of Colon
Malignant Neoplasm Of Pancreas
Carcinogenesis
Malignant Paraganglionic Neoplasm
Adenocarcinoma Of Lung (disorder)
Adenoma

Interacting Proteins

Fnta
RAF1
RASSF2

Pathways

Methylation
Pathogenesis
Cell Proliferation
Mismatch Repair
Cell Growth
Dna Methylation
Cell Cycle
Angiogenesis
Localization
Dna Repair
Cell Death
Oncogenesis
Senescence

Drug Resistance
Translation
Rna Interference
Gene Silencing
Cell Cycle Arrest
Cell Differentiation
Immune Response

PTMs

Methylation
Phosphorylation
Cleavage
Dephosphorylation
Demethylation
Farnesylation
Prenylation
Ubiquitination
Acetylation

Biotinylation
Sumoylation
Carboxylation
Depalmitoylation
Deamination
Citrullination
Reduction
Glycosylation
Palmitoylation

Research Areas

Cell Cycle and Replication
Core ESC-Like Genes
mTOR Pathway
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRAS

References

PMID: 6308466 by McGrath J.P., et al. Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene.

PMID: 6308465 by Shimizu K., et al. Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1.

1 Publications of Boster GTPase KRas Antibodies & ELISA Kits

PubMed ID: 17118848, Li M, Liu W, Zhu Yf, Chen Yl, Zhang Bz, Wang R. Acta Oncol. 2006;45(8):1115-9. C...

*More publications can be found for each product on its corresponding product page