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- Table of Contents
KRT4 Antibodies
AND KRT4 ELISA kits, KRT4 Proteins
Many biological assays use antibodies to detect KRT4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRT4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRT4 antibodies...
Designing a Western blot for KRT4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the KRT4 Western Blot GuideDesigning an IHC experiment for KRT4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the KRT4 IHC GuideKRT4 Infographic by Boster Bio
All KRT4 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, IF, IHC, WB
$370
Cat # A07410-3
100 µg/vial
Cat # A07410-3
100 µg/vial
Human, Rat
IF, IHC, ICC, WB
$370
Cat # M07410
100 μl
Cat # M07410
100 μl
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M07410-1
100 μl
Cat # M07410-1
100 μl
KRT4 Overview
Facts about Keratin, type II cytoskeletal 4.
Keratin, type II cytoskeletal 4 (KRT4)
Gene Information
| Human | |
|---|---|
| Gene Name: | KRT4 |
| Uniprot: | P19013 |
| Entrez: | 3851 |
Family
| Belongs to: |
|---|
| intermediate filament family |
Alternative Names
CK4; CK-4; CYK4cytokeratin-4; Cytokeratin-4; FLJ31692; K4cytokeratin 4; keratin 4; keratin, type II cytoskeletal 4; Keratin-4; Type-II keratin Kb4
Molecular Weight
Mass (kDA):
56.144 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.13 |
| Sequence: | 12; NC_000012.12 (52806549..52814116, complement) |
Tissue Specificity
Detected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa (at protein level). Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer.
Diseases
- Malignant Neoplasms
- Carcinoma
- Neoplasms
- Malignant Squamous Cell Neoplasm
- Inflammation
- Malignant Neoplasm Of Ovary
- Cell Invasion
- Mouth Neoplasms
- Ovarian Neoplasm
- Esophageal Neoplasms
- Malignant Paraganglionic Neoplasm
- Neoplasm Metastasis
- Coronary Heart Disease
Interacting Proteins
- KRT15
- KRT33B
- KRT38
- KRT40
- TRIM54
Pathways
- Keratinization
- Keratinocyte Differentiation
- Localization
- Transport
- Gastrulation
- Cell Proliferation
- Cell Migration
- Gene Silencing
- Lung Development
- Proteolysis
- Blood Circulation
- Epiboly
- Drug Resistance
PTMs
Research Areas
- Cancer
- Cell Biology
- Cellular Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRT4
bosterbio.com/bosterbio-gene-info-cards/KRT4
References
PMID: 7684424 by Wanner R., et al. Allelic variations of human keratins K4 and K5 provide polymorphic markers within the type II keratin gene cluster on chromosome 12.
PMID: 2452170 by Leube R.E., et al. Molecular characterization and expression of the stratification- related cytokeratins 4 and 15.
1 Publications of Boster KRT4 Antibodies & ELISA Kits
- PubMed ID: 10.3892/or.2018.6610, Screening diagnostic biomarkers of OSCC via an LCM-based proteomic approach
*More publications can be found for each product on its corresponding product page