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- Table of Contents
KRT6A Antibodies
AND KRT6A ELISA kits, KRT6A Proteins
Many biological assays use antibodies to detect KRT6A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRT6A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRT6A antibodies...
Designing a Western blot for KRT6A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the KRT6A Western Blot GuideDesigning an IHC experiment for KRT6A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the KRT6A IHC GuideKRT6A Infographic by Boster Bio
All KRT6A Products
Product
Figures
Specificity
Applications
Price
Human, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04012-2
100 μl/vial
Cat # A04012-2
100 μl/vial
KRT6A Overview
Facts about Keratin, type II cytoskeletal 6A.
Keratin, type II cytoskeletal 6A (KRT6A)
Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration.
Participates in the regulation of epithelial migration by inhibiting the action of SRC during wound repair. .
Gene Information
| Human | |
|---|---|
| Gene Name: | KRT6A |
| Uniprot: | P02538 |
| Entrez: | 3853 |
Family
| Belongs to: |
|---|
| intermediate filament family |
Alternative Names
Allergen Hom s 5; CK6A; CK-6A; CK6C; CK6D; CK-6D; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; Cytokeratin-6A; Cytokeratin-6D; K6A; K6C; K6D; keratin 6A; keratin 6C; keratin 6D; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 6A; Keratin-6A; KRT6C; KRT6D; Type-II keratin Kb6
Molecular Weight
Mass (kDA):
60.045 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.13 |
| Sequence: | 12; NC_000012.12 (52487176..52493257, complement) |
Tissue Specificity
Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.
Diseases
- Pachyonychia Congenita
- Thickened Nails
- Carcinoma
- Dermatologic Disorders
- Malignant Neoplasms
- Dystrophy
- Palmoplantar Keratosis
- Dystrophia Unguium
- Neoplasms
- Hypertrophy
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
Interacting Proteins
- CCDC85B
- GOLGA2
- HGS
- KIFC3
- KRT13
- KRT15
- KRT31
- KRT38
- KRT40
- SGTA
Pathways
- Wound Healing
- Rna Interference
- Keratinization
- Translation
- Cell Growth
- Cell Adhesion
- Cell Migration
- Cytolysis
- Cell Proliferation
- Cornification
- Aging
PTMs
Research Areas
- Cell Biology
- Cellular Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRT6A
bosterbio.com/bosterbio-gene-info-cards/KRT6A
References
PMID: 7543104 by Takahashi K., et al. Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.
PMID: 6191871 by Hanukoglu I., et al. The cDNA sequence of a type II cytoskeletal keratin reveals constant and variable structural domains among keratins.