LAPTM5 Antibodies

AND LAPTM5 ELISA kits, LAPTM5 Proteins

Many biological assays use antibodies to detect LAPTM5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LAPTM5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LAPTM5 antibodies...

We validate the specificity of these antibodies to LAPTM5 by testing them on tissues known to express LAPTM5 positively and negatively. Browse below to find the LAPTM5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for LAPTM5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LAPTM5 IHC Guide

LAPTM5 Infographic by Boster Bio

All LAPTM5 Products

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Product

Figures

Specificity

Applications

Price

Anti-LAPTM5 Antibody (N-term)

LAPTM5 Antibody (N-term) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A09673
80 µl

LAPTM5 (NM_006762) Human Over-expression Lysate

Human

$628
Cat # LS007805
20 µg, 100 µg

LAPTM5 (NM_006762) Human Recombinant Protein

Coomassie blue staining of purified LAPTM5 protein

$1249
Cat # PROTQ13571
20 µg

LAPTM5 Overview

Facts about Lysosomal-associated transmembrane protein 5.

LAPTM5 3D structure. Source: alphafold

Lysosomal-associated transmembrane protein 5 (LAPTM5)

May have a distinctive functional role during embryogenesis and in adult hematopoietic cells. .

Gene Information

Human
Gene Name:	LAPTM5
Uniprot:	Q13571
Entrez:	7805

Family

Belongs to:

LAPTM4/LAPTM5 transporter family

Alternative Names

CD40-ligand-activated specific transcripts; CLAST6; FLJ61683; FLJ97251; human retinoic acid-inducible E3 protein; KIAA0085; lysosomal associated multispanning membrane protein 5; lysosomal multispanning membrane protein 5; lysosomal protein transmembrane 5; Lysosomal-associated multitransmembrane protein 5; lysosomal-associated transmembrane protein 5; MGC125860; MGC125861; Retinoic acid-inducible E3 protein

Molecular Weight

Mass (kDA):
29.937 kDA

Genomic Context


Human

Location:	1p35.2
Sequence:	1; NC_000001.11 (30732469..30757840, complement)

Tissue Specificity

Preferentially expressed in adult hematopoietic tissues. High levels in lymphoid and myeloid tissues. Highly expressed in peripheral blood leukocytes, thymus, spleen and lung, followed by placenta, liver and kidney.

Subcellular Localizations

Lysosome membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Inflammation
Neoplasms
Liver Carcinoma
Liver Neoplasms
Autoimmunity
Carcinoma
Acute Promyelocytic Leukemia
Lymphoma
Rheumatoid Arthritis
Arthritis
Chromosomal Translocation
Neuroblastoma

Cell Transformation, Neoplastic
Lung Neoplasms
Fracture Of First Cervical Vertebra
Melanoma
Malignant Neoplasm Of Breast
Mucolipidosis Type Iv
Nerve Transections, Optic

Interacting Proteins

DISP1
LDLRAD1

Pathways

Cell Activation
Dna Methylation
Methylation
Transport
B Cell Activation
Cell Death
Pathogenesis
Programmed Cell Death
T Cell Activation
Localization
Cytokine Secretion
Lung Development
Reverse Transcription

Phagocytosis
Cell Differentiation
Cell-cell Adhesion
Oncogenesis
Autophagic Cell Death
Cell Development
Lysosomal Transport

PTMs

Ubiquitination

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LAPTM5

References

PMID: 8661146 by Adra C.N., et al. LAPTM5: a novel lysosomal-associated multispanning membrane protein preferentially expressed in hematopoietic cells.