Product Info Summary
SKU: | A09673 |
---|---|
Size: | 80 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | Flow Cytometry, IHC-P, WB |
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Product info
Product Name
Anti-LAPTM5 Antibody (N-term)
SKU/Catalog Number
A09673
Size
80 µl
Description
Boster Bio Anti-LAPTM5 Antibody (N-term) (Catalog # A09673). Tested in WB, Flow Cytometry, IHC-P application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-LAPTM5 Antibody (N-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09673)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This LAPTM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human LAPTM5.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09673 is reactive to LAPTM5 in Human
Reconstitution
Calculated molecular weight
29937 Da
Background of LAPTM5
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09673 is guaranteed for Flow Cytometry, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
IHC-P: 1:50-1:100
FC: 1:10-1:50
Validation Images & Assay Conditions
Click image to see more details
All lanes : Anti-LAPTM5 Antibody (N-term) at 1:1000 dilution
Lane 1: U266B1 whole cell lysate
Lane 2: Jurkat whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 30 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Click image to see more details
LAPTM5 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph node followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LAPTM5 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Click image to see more details
LAPTM5 Antibody (N-term) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Protein Target Info & Infographic
Gene/Protein Information For LAPTM5 (Source: Uniprot.org, NCBI)
Gene Name
LAPTM5
Full Name
Lysosomal-associated transmembrane protein 5
Weight
29937 Da
Superfamily
LAPTM4/LAPTM5 transporter family
Alternative Names
Lysosomal-associated transmembrane protein 5, Lysosomal-associated multitransmembrane protein 5, Retinoic acid-inducible E3 protein, LAPTM5, KIAA0085 LAPTM5 CLAST6 lysosomal protein transmembrane 5 lysosomal-associated transmembrane protein 5|CD40-ligand-activated specific transcripts|human retinoic acid-inducible E3 protein|lysosomal associated multispanning membrane protein 5|lysosomal multispanning membrane protein 5|lysosomal-associated multitransmembrane protein 5|retinoic acid-inducible E3 protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LAPTM5, check out the LAPTM5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LAPTM5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-LAPTM5 Antibody (N-term) (A09673)
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