LEMD2 Antibodies

AND LEMD2 ELISA kits, LEMD2 Proteins

Many biological assays use antibodies to detect LEMD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LEMD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LEMD2 antibodies...

We validate the specificity of these antibodies to LEMD2 by testing them on tissues known to express LEMD2 positively and negatively. Browse below to find the LEMD2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LEMD2 Infographic by Boster Bio

All LEMD2 Products

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Specificity

Applications

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Anti-LEMD2 Antibody

Western blot analysis of LEMD2 in 293 cell lysate with LEMD2 antibody at (A) 1 and (B) 2 μg/mL

Immunocytochemistry of LEMD2 in 3T3 cells with LEMD2 antibody at 2

Immunofluorescence of LEMD2 in 3T3 cells with LEMD2 antibody at 20 μg/mL

Human, Mouse

ELISA, IF, ICC, WB

$481
Cat # A09079
0.1 mg

LEMD2 (NM_181336) Human Recombinant Protein

Coomassie blue staining of purified LEMD2 protein

$1249
Cat # PROTQ8NC56
20 µg

LEMD2 (NM_181336) Human Over-expression Lysate

Human

$628
Cat # LS221496
20 µg, 100 µg

LEMD2 Overview

Facts about LEM domain-containing protein 2.

LEMD2 3D structure. Source: alphafold

LEM domain-containing protein 2 (LEMD2)

Involved in nuclear structure organization (PubMed:16339967). Required for maintaining the integrity of the nuclear envelope (PubMed:17097643).

Gene Information

Human
Gene Name:	LEMD2
Uniprot:	Q8NC56
Entrez:	221496

Family

Belongs to:

No superfamily

Alternative Names

LEM domain containing 2

Molecular Weight

Mass (kDA):
56.975 kDA

Genomic Context


Human

Location:	6p21.31
Sequence:	6; NC_000006.12 (33771213..33794274, complement)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus inner membrane; Multi-pass membrane protein. Lamina-associated protein residing in the inner nuclear membrane (INM). Localized exclusively to the nuclear envelope, giving rise to a typical rim-like staining of the nuclear periphery.

Diseases

X-linked Emery-dreifuss Muscular Dystrophy
Muscular Dystrophy, Emery-dreifuss
Bone Diseases
Dystrophy
Muscular Dystrophy

Pathways

Myoblast Differentiation
Rna Interference

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LEMD2

References

PMID: 16339967 by Brachner A., et al. LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type lamins.

PMID: 17097643 by Ulbert S., et al. The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology.