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- Table of Contents
LIAS Antibodies
AND LIAS ELISA kits, LIAS Proteins
Many biological assays use antibodies to detect LIAS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LIAS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LIAS antibodies...
Designing a Western blot for LIAS? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the LIAS Western Blot GuideDesigning an IHC experiment for LIAS? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the LIAS IHC GuideLIAS Infographic by Boster Bio
All LIAS Products
Product
Figures
Specificity
Applications
Price
LIAS Overview
Facts about Lipoyl synthase, mitochondrial.
Lipoyl synthase, mitochondrial (LIAS)
Catalyzes the radical-mediated insertion of two sulfur atoms to the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LIAS |
| Uniprot: | O43766 |
| Entrez: | 11019 |
Family
| Belongs to: |
|---|
| radical SAM superfamily |
Alternative Names
EC 2.8.1.8; LASmitochondrial; LIP1; lipoic acid synthetase; Lip-syn; MGC23245
Molecular Weight
Mass (kDA):
41.911 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4p14 |
| Sequence: | 4; NC_000004.12 (39459024..39479506) |
Subcellular Localizations
Mitochondrion.
Diseases
- Diabetes Mellitus
- Dental Caries
- Atherosclerosis
- Diabetic Nephropathy
- Diabetes Mellitus, Experimental
- Dental Plaque
- Streptococcal Infections
- Kidney Diseases
- Dyslipidemias
- Swine Vesicular Disease
- Brain Ischemia
- Diabetic Neuropathies
Pathways
- Virulence
- Biofilm Formation
- Pathogenesis
- Sensitization
- Hypersensitivity
- Forebrain Development
PTMs
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LIAS
bosterbio.com/bosterbio-gene-info-cards/LIAS
References
PMID: 11124703 by Stanchi F., et al. Characterization of 16 novel human genes showing high similarity to yeast sequences.
PMID: 22152680 by Mayr J.A., et al. Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation.