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- Table of Contents
Hormone-sensitive lipase Antibodies
AND LIPE ELISA kits, Hormone-sensitive lipase Proteins
Many biological assays use antibodies to detect Hormone-sensitive lipase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hormone-sensitive lipase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hormone-sensitive lipase antibodies...
Designing an IHC experiment for Hormone-sensitive lipase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the LIPE IHC GuideLIPE Infographic by Boster Bio
All LIPE Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # P06762-1
100 μl
Cat # P06762-1
100 μl
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A06762
0.1 mg
Cat # A06762
0.1 mg
Human, Mouse, Rat
ELISA
$540
Cat # EKC2040
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2040
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1988
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1988
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1285
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1285
1 kit, containing one 96-well plate and all necessary reagents
Human
$628
Cat # LS003991
20 µg, 100 µg
Cat # LS003991
20 µg, 100 µg
LIPE Overview
Facts about Hormone-sensitive lipase.
Hormone-sensitive lipase (LIPE)
In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic cells, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LIPE |
| Uniprot: | Q05469 |
| Entrez: | 3991 |
Family
| Belongs to: |
|---|
| GDXG' lipolytic enzyme family |
Alternative Names
hormone-sensitive lipase testicular isoform; Hormonesensitive Lipase; Hormone-sensitive Lipase; HSL; HSLEC 3.1.1.79; LHS; lipase, hormone-sensitive; LIPE
Molecular Weight
Mass (kDA):
116.598 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.2 |
| Sequence: | 19; NC_000019.10 (42401512..42427421, complement) |
Subcellular Localizations
Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation.
Diseases
- Obesity
- Insulin Resistance
- Infertility
- Male Infertility
- Atherosclerosis
- Dyslipidemias
- Dysequilibrium Syndrome
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Obesity, Abdominal
- African Swine Fever
- Insulin Sensitivity
- Cholangiocarcinoma
Pathways
- Transport
- Localization
- Secretion
- Lipid Storage
- Cholesterol Transport
- Lactation
- Oxidative Phosphorylation
- Hepatocyte Proliferation
- Spermatogenesis
- Glucose Homeostasis
- Regulation Of Hepatocyte Proliferation
- Fatty Acid Transport
- Cholesterol Efflux
PTMs
- Phosphorylation
- Oxidation
Research Areas
- Cancer
- Cholesterol Metabolism
- Diabetes Research
- Lipid and Metabolism
- Lipid Droplets
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LIPE
bosterbio.com/bosterbio-gene-info-cards/LIPE
References
PMID: 8506334 by Langin D., et al. Gene organization and primary structure of human hormone-sensitive lipase: possible significance of a sequence homology with a lipase of Moraxella TA144, an antarctic bacterium.
PMID: 8812477 by Holst L.S., et al. Molecular cloning, genomic organization, and expression of a testicular isoform of hormone-sensitive lipase.