Lysyl oxidase homolog 1 Antibodies

AND LOXL1 ELISA kits, Lysyl oxidase homolog 1 Proteins

Many biological assays use antibodies to detect Lysyl oxidase homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lysyl oxidase homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lysyl oxidase homolog 1 antibodies...

We validate the specificity of these antibodies to Lysyl oxidase homolog 1 by testing them on tissues known to express LOXL1 positively and negatively. Browse below to find the LOXL1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Lysyl oxidase homolog 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the LOXL1 Western Blot Guide

Designing an IHC experiment for Lysyl oxidase homolog 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LOXL1 IHC Guide

LOXL1 Infographic by Boster Bio

All LOXL1 Products

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Product

Figures

Specificity

Applications

Price

Anti-LOXL1 Antibody Picoband®

5 Citations

Western blot analysis of LOXL1 using anti-LOXL1 antibody (PB9719)

IHC analysis of LOXL1 using anti-LOXL1 antibody (PB9719)

Immunohisctochemical detection of risk gene in GBM tissues

Human

IHC, WB

$370
Cat # PB9719
100 μg/vial

LOXL1 (NM_005576) Human Over-expression Lysate

Human

$628
Cat # LS004016
20 µg, 100 µg

LOXL1 Overview

Facts about Lysyl oxidase homolog 1.

LOXL1 3D structure. Source: alphafold

Lysyl oxidase homolog 1 (LOXL1)

Active on elastin and collagen substrates. .

Gene Information

Human
Gene Name:	LOXL1
Uniprot:	Q08397
Entrez:	4016

Family

Belongs to:

lysyl oxidase family

Alternative Names

EC 1.4.3.13; LOLEC 1.4.3; LOXL; LOXL1; LOXLEC 1.4.3.-; Lysyl Oxidase Homolog 1; Lysyl Oxidase like 1; lysyl oxidase-like 1; Lysyl oxidase-like protein 1

Molecular Weight

Mass (kDA):
63.11 kDA

Genomic Context


Human

Location:	15q24.1
Sequence:	15; NC_000015.10 (73926462..73952137)

Tissue Specificity

Expressed in ocular tissues including the iris, ciliary body, lens and optic nerve. Not detected in the retina.

Subcellular Localizations

Secreted, extracellular space.

Diseases

Exfoliation Syndrome
Glaucoma
Glaucoma, Open-angle
Primary Open Angle Glaucoma
Intraocular Pressure Disorder
Blepharoptosis
Pelvic Organ Prolapse
Malignant Neoplasms
Uterine Prolapse
Neoplasms
Cataract
Dysequilibrium Syndrome
Nerve Damage

Atherosclerosis
Vascular Diseases
Alzheimer's Disease
Urinary Incontinence
Age Related Macular Degeneration
Angle Closure Glaucoma
Cutis Laxa

Pathways

Pathogenesis
Aging
Elastic Fiber Assembly
Localization
Parturition
Methylation
Cell Adhesion
Dna Methylation
Notochord Development
Keratinization
Dna Hypermethylation
Gene Silencing
Cellular Senescence

Lung Development
Pigmentation
Spermatogenesis
Chemotaxis
Cell Cycle
Menopause
Endocytosis

PTMs

Cleavage
Methylation

Deamination
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LOXL1

References

PMID: 7689553 by Kenyon K., et al. A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25.

PMID: 17690259 by Thorleifsson G., et al. Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma.