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Apolipoprotein(a) Antibodies
AND LPA ELISA kits, Apolipoprotein(a) Proteins
Many biological assays use antibodies to detect Apolipoprotein(a), such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Apolipoprotein(a) in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Apolipoprotein(a) antibodies...
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LPA Overview
Facts about Apolipoprotein(a).
Apolipoprotein(a) (LPA)
Apo(a) is the principal constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis.
Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.
Gene Information
| Human | |
|---|---|
| Gene Name: | LPA |
| Uniprot: | P08519 |
| Entrez: | 4018 |
Family
| Belongs to: |
|---|
| peptidase S1 family |
Alternative Names
AK38; antiangiogenic AK38 protein; Apo(a); APOA; apolipoprotein(a); EC 3.4.21; EC 3.4.21.-; EC 3.4.21.7; lipoprotein, Lp(a); LP; lp(a)
Molecular Weight
Mass (kDA):
501.319 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q25.3-q26 |
| Sequence: | 6; NC_000006.12 (160531482..160664275, complement) |
Diseases
- Malignant Neoplasms
- Neoplasms
- Pertussis
- Tissue Adhesions
- Cell Invasion
- Malignant Neoplasm Of Ovary
- Neoplasm Metastasis
- Ovarian Neoplasm
- Inflammation
- Carcinoma
- Neoplasm Invasiveness
- Tumor Angiogenesis
- Nervousness
Interacting Proteins
- APOH
- FN1
Pathways
- Cell Proliferation
- Cell Migration
- Secretion
- Angiogenesis
- Wound Healing
- Cell Growth
- Cell Motility
- Localization
- Chemotaxis
- Pathogenesis
- Lymphocyte Proliferation
- Platelet Aggregation
- Cell Adhesion
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
- Acylation
- Ribosylation
- Oxidation
- Acetylation
- Biotinylation
- Glycosylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LPA
bosterbio.com/bosterbio-gene-info-cards/LPA
References
PMID: 3670400 by McLean J.W., et al. cDNA sequence of human apolipoprotein(a) is homologous to plasminogen.
PMID: 7848387 by Pfaffinger D., et al. Amplification of human APO(a) kringle 4-37 from blood lymphocyte DNA.