LSM8 Antibodies

AND LSM8 ELISA kits, LSM8 Proteins

Many biological assays use antibodies to detect LSM8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LSM8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LSM8 antibodies...

We validate the specificity of these antibodies to LSM8 by testing them on tissues known to express LSM8 positively and negatively. Browse below to find the LSM8 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for LSM8? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the LSM8 Western Blot Guide

LSM8 Infographic by Boster Bio

All LSM8 Products

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Product

Figures

Specificity

Applications

Price

Anti-LSM8 Antibody Picoband®

Western blot analysis of LSM8 using anti-LSM8 antibody (A10947)

IHC analysis of LSM8 using anti-LSM8 antibody (A10947)

+10

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A10947
100 μg/vial

Anti-LSM8 Antibody Picoband® (monoclonal, 6B11)

Western blot analysis of LSM8 using anti-LSM8 antibody (M10947)

IHC analysis of LSM8 using anti-LSM8 antibody (M10947)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M10947
100 μg/vial

LSM8 (NM_016200) Human Over-expression Lysate

Human

$628
Cat # LS051691
20 µg, 100 µg

LSM8 Overview

Facts about U6 snRNA-associated Sm-like protein LSm8.

LSM8 3D structure. Source: alphafold

U6 snRNA-associated Sm-like protein LSm8 (LSM8)

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).

Gene Information

Human
Gene Name:	LSM8
Uniprot:	O95777
Entrez:	51691

Family

Belongs to:

snRNP Sm proteins family

Alternative Names

U6 snRNA-associated Sm-like protein LSm8

Molecular Weight

Mass (kDA):
10.403 kDA

Genomic Context


Human

Location:	7q31.31
Sequence:	7; NC_000007.14 (118184164..118204035)

Subcellular Localizations

Nucleus.

Interacting Proteins

LSM2
LSM3
LSM4
LSM6

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LSM8

References

PMID: 10523320 by Achsel T., et al. A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

PMID: 26912367 by Agafonov D.E., et al. Molecular architecture of the human U4/U6.U5 tri-snRNP.