LYST Antibodies

AND LYST ELISA kits, LYST Proteins

Many biological assays use antibodies to detect LYST, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LYST in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LYST antibodies...

We validate the specificity of these antibodies to LYST by testing them on tissues known to express LYST positively and negatively. Browse below to find the LYST antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LYST Infographic by Boster Bio

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LYST Overview

Facts about Lysosomal-trafficking regulator.

Lysosomal-trafficking regulator (LYST)

Might be required for sorting endosomal resident proteins to late multivesicular endosomes by a mechanism involving microtubules. .

Gene Information

Human
Gene Name:	LYST
Uniprot:	Q99698
Entrez:	1130

Family

Belongs to:

No superfamily

Alternative Names

Beige homolog; Chediak-Higashi syndrome 1; CHSCHS1beige protein; lysosomal trafficking regulator; lysosomal-trafficking regulator

Molecular Weight

Mass (kDA):
429.139 kDA

Genomic Context


Human

Location:	1q42.3
Sequence:	1; NC_000001.11 (235661031..235883713, complement)

Tissue Specificity

Abundantly expressed in adult and fetal thymus, peripheral blood leukocytes, bone marrow and several regions of the adult brain.

Subcellular Localizations

Cytoplasm.

Diseases

Chediak-higashi Syndrome
Immunologic Deficiency Syndromes
Albinism
Hemorrhage
Infective Disorder
Albinism, Oculocutaneous
Lymphohistiocytosis, Hemophagocytic
Hypopigmentation Disorder
Bleeding Tendency
Hermanski-pudlak Syndrome
Hereditary Diseases
Lymphoproliferative Disorders

Neoplasms
Severe Combined Immunodeficiency
Hypopigmentation-immunodeficiency Disease
Virus Diseases
Malignant Neoplasms
Piebaldism
Peripheral Neuropathy

Pathways

Secretion
Transport
Pigmentation
Exocytosis
Endocytosis
Localization
Pathogenesis
Vesicle Fusion
Immune Response
Cytokinesis
Chemotaxis
Intracellular Transport
Secretory Pathway

Cytolysis
Macrophage Activation
Cell Activation
Cell Migration
Neutrophil Differentiation
T Cell Activation
Leukocyte Migration

PTMs

Phosphorylation
Cleavage

Prenylation
Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LYST

References

PMID: 8896560 by Nagle D.L., et al. Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome.

PMID: 8717042 by Barbosa M.D.F.S., et al. Identification of the homologous beige and Chediak-Higashi syndrome genes.