- Table of Content
May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for following re-uptake and degradation in lymph nodes. .
|Sequence:||11; NC_000011.10 (10556966..10568665, complement)|
Mainly expressed in endothelial cells lining lymphatic vessels.
Membrane; Single-pass type I membrane protein. Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
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