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- Table of Contents
LYVE1 Antibodies
AND LYVE1 ELISA kits, LYVE1 Proteins
Many biological assays use antibodies to detect LYVE1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LYVE1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LYVE1 antibodies...
Designing a Western blot for LYVE1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the LYVE1 Western Blot GuideLYVE1 Infographic by Boster Bio
All LYVE1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M04027-2
20μL, 40μL, 100μL, 200μL
Cat # M04027-2
20μL, 40μL, 100μL, 200μL
LYVE1 Overview
Facts about Lymphatic vessel endothelial hyaluronic acid receptor 1.
Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1)
Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS).
May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for following re-uptake and degradation in lymph nodes. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LYVE1 |
| Uniprot: | Q9Y5Y7 |
| Entrez: | 10894 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
cell surface retention sequence binding protein-1; Cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extracellular link domain containing 1; extracellular link domain-containing 1; Extracellular link domain-containing protein 1; HAR; Hyaluronic acid receptor; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; LYVE-1XLKD1; XLKD1
Molecular Weight
Mass (kDA):
35.213 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.4 |
| Sequence: | 11; NC_000011.10 (10556966..10568665, complement) |
Tissue Specificity
Mainly expressed in endothelial cells lining lymphatic vessels.
Subcellular Localizations
Membrane; Single-pass type I membrane protein. Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
Diseases
- Neoplasms
- Neoplasm Metastasis
- Malignant Neoplasms
- Lymphatic Metastasis
- Metastatic Malignant Neoplasm To The Lymph Node
- Carcinoma
- Cell Invasion
- Pathologic Neovascularization
- Tumor Angiogenesis
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Inflammation
Interacting Proteins
- KRTAP10-8
Pathways
- Lymphangiogenesis
- Angiogenesis
- Secretion
- Pathogenesis
- Transport
- Cell Adhesion
- Cell Migration
- Localization
- Cell Proliferation
- Wound Healing
- Cell Growth
- Regulation Of Lymphangiogenesis
- Tube Formation
PTMs
- Sulphation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LYVE1
bosterbio.com/bosterbio-gene-info-cards/LYVE1
References
PMID: 10037799 by Banerji S., et al. LYVE-1, a new homologue of the CD44 glycoprotein is a lymph-specific receptor for hyaluronan.
2 Publications of Boster LYVE1 Antibodies & ELISA Kits
- PubMed ID: 16124044, Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 an...
- PubMed ID: 24502459, Du Lc, Chen Xc, Wang D, Wen Yj, Wang Ct, Wang Xm, Kan B, Wei Yq, Zhao X. Reprod ...
*More publications can be found for each product on its corresponding product page