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- Table of Contents
Lef1 Antibodies
AND Lef1 ELISA kits, Lef1 Proteins
Many biological assays use antibodies to detect Lef1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lef1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lef1 antibodies...
Designing a Western blot for Lef1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the LEF1 Western Blot GuideDesigning an IHC experiment for Lef1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the LEF1 IHC GuideLef1 Infographic by Boster Bio
All Lef1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00605-2
100 μg/vial
Cat # A00605-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00605
100 μl
Cat # M00605
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00605-3
20μL, 40μL, 100μL, 200μL
Cat # M00605-3
20μL, 40μL, 100μL, 200μL
Lef1 Overview
Facts about Lymphoid enhancer-binding factor 1.
Lymphoid enhancer-binding factor 1 (Lef1)
TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1 (By similarity). Regulates T-cell receptor alpha enhancer function.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Lef1 |
| Uniprot: | P27782 |
| Entrez: | 16842 |
Family
| Belongs to: |
|---|
| TCF/LEF family |
Alternative Names
DKFZp586H0919; FLJ46390; LEF1; LEF-1; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
Molecular Weight
Mass (kDA):
44.059 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 3 G3|3 60.78 cM |
| Sequence: | 3; |
Tissue Specificity
Lymphocytes. Found in distinct epithelial cell compartments of the skin and is abundant in the hair-producing progenitors of the follicle.
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Carcinoma
- Malignant Tumor Of Colon
- Leukemia
- Tissue Adhesions
- Colonic Neoplasms
- Malignant Paraganglionic Neoplasm
- Skin Neoplasms
- Crest Syndrome
- Adenomatous Polyposis Coli
- Cell Invasion
Pathways
- Cell Proliferation
- Localization
- Cell Cycle
- Pathogenesis
- Cell Differentiation
- Regeneration
- Cell Growth
- Cell Adhesion
- Gland Development
- Methylation
- Cell Development
- Mammary Gland Development
- Anagen
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Cleavage
- Sumoylation
- Demethylation
Research Areas
- DNA Repair
- DNA replication, Transcription, Translation and Splicing
- Signal Transduction
- Transcription Factors and Regulators
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lef1
bosterbio.com/bosterbio-gene-info-cards/Lef1
References
PMID: 1827423 by Travis A., et al. LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function.
PMID: 8415007 by Fujimoto S., et al. Nucleotide sequence of a cDNA encoding an alternative form of LEF- 1.