LEFTY1 Antibodies

AND LEFTY1 ELISA kits, LEFTY1 Proteins

Many biological assays use antibodies to detect LEFTY1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LEFTY1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LEFTY1 antibodies...

We validate the specificity of these antibodies to LEFTY1 by testing them on tissues known to express LEFTY1 positively and negatively. Browse below to find the LEFTY1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LEFTY1 Infographic by Boster Bio

All LEFTY1 Products

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Applications

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Anti-Lefty LEFTY1 Antibody

4 Q&As

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung

Western Blot analysis of HepG2-UV cells using Lefty Polyclonal Antibody

Western Blot analysis of HEPG2-UV cells using Lefty Polyclonal Antibody diluted at 1:500

Human, Mouse

IHC, WB

$399
Cat # A05889
100μl

Anti-LEFTY1 Antibody

Western blot analysis of extracts of various cell lines, using LEFTY1 antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A05889-1
100ul

Lefty (LEFTY1) (NM_020997) Human Over-expression Lysate

Human

$628
Cat # LS010637
20 µg, 100 µg

Human Lefty ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2236
96 wells/kit, with removable strips.

LEFTY1 Overview

Facts about Left-right determination factor 1.

LEFTY1 3D structure. Source: alphafold

Left-right determination factor 1 (LEFTY1)

Required for left-right axis determination as a regulator of LEFTY2 and NODAL.
.

Gene Information

Human
Gene Name:	LEFTY1
Uniprot:	O75610
Entrez:	10637

Family

Belongs to:

TGF-beta family

Alternative Names

AI450052; EBAF; Leftb; lefty; Lefty1; Lefty-1; Lefty-B; Stra3; TGFB4

Molecular Weight

Mass (kDA):
40.88 kDA

Genomic Context


Human

Location:	1q42.12
Sequence:	1; NC_000001.11 (225886282..225889146, complement)

Subcellular Localizations

Secreted.

Diseases

Congenital Heart Defects
Neoplasms
Cyclocephaly
Congenital Abnormality
Malignant Neoplasms
Situs Ambiguus
Teratoma
Endometrial Polyp
Teratocarcinoma
Situs Inversus
Neoplasm Metastasis
Embryonal Carcinoma
Melanoma

Infertility
Carcinoma
Immunologic Deficiency Syndromes
Dysplasia
Fibrosis
Hemorrhage
Collagenolysis

Pathways

Gastrulation
Heart Looping
Axis Specification
Embryo Implantation
Segmentation
Dna Methylation
Primitive Streak Formation
Nodal Signaling Pathway
Cell Development
Methylation
Heart Morphogenesis
Cell Differentiation
Germ Cell Development

Transport
Stem Cell Differentiation
Menstruation
Cell Cycle
Localization
Decidualization
Hair Follicle Development

PTMs

Phosphorylation
Cleavage

Methylation
Demethylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LEFTY1

References

PMID: 10053005 by Kosaki K., et al. Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.