MAP3K6 Antibodies

AND MAP3K6 ELISA kits, MAP3K6 Proteins

Many biological assays use antibodies to detect MAP3K6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAP3K6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAP3K6 antibodies...

We validate the specificity of these antibodies to MAP3K6 by testing them on tissues known to express MAP3K6 positively and negatively. Browse below to find the MAP3K6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MAP3K6 Infographic by Boster Bio

All MAP3K6 Products

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Product

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Specificity

Applications

Price

Anti-MEK Kinase-6 MAP3K6 Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MAP3K6 Antibody

Human, Mouse

ELISA, IF, IHC

$380
Cat # A09063
100ul

MAP3K6 (NM_004672) Human Over-expression Lysate

Human

$960
Cat # LS009064
20 µg, 100 µg

MAP3K6 Overview

Facts about Mitogen-activated protein kinase kinase kinase 6.

MAP3K6 3D structure. Source: alphafold

Mitogen-activated protein kinase kinase kinase 6 (MAP3K6)

Part of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.

Gene Information

Human
Gene Name:	MAP3K6
Uniprot:	O95382
Entrez:	9064

Family

Belongs to:

protein kinase superfamily

Alternative Names

apoptosis signal regulating kinase 2; ASK2MGC20114; EC 2.7.11; EC 2.7.11.25; MAPKKK6MEKK6Apoptosis signal-regulating kinase 2; MGC125653; mitogen-activated protein kinase kinase kinase 6

Molecular Weight

Mass (kDA):
142.596 kDA

Genomic Context


Human

Location:	1p36.11
Sequence:	1; NC_000001.11 (27355179..27368037, complement)

Diseases

Ischemia
Neoplasms
Stomach Neoplasms
Cell Transformation, Neoplastic
Brain Ischemia
Hypoxia
Inflammatory Response
Pneumonia
Inhalation Exposure
Tumor Angiogenesis
Malignant Neoplasm Of Stomach
Acute-phase Reaction

Cardiomyopathies
Malignant Neoplasms
Cardiotoxicity
Inflammation
Pathologic Neovascularization
Stress, Psychological
Growth Arrest

Pathways

Cell Death
Immune Response
Angiogenesis
Inflammatory Response

PTMs

Phosphoprotein

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAP3K6

References

PMID: 17210579 by Takeda K., et al. Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen- activated protein kinase kinase kinase in a heteromeric complex with ASK1.

PMID: 9875215 by Wang X.S., et al. MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5.