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- Table of Contents
Facts about MAP/microtubule affinity-regulating kinase 3.
Phosphorylates the microtubule- associated protein MAPT/TAU (PubMed:23666762). Phosphorylates CDC25C on 'Ser-216'.
| Human | |
|---|---|
| Gene Name: | MARK3 |
| Uniprot: | P27448 |
| Entrez: | 4140 |

| Belongs to: |
|---|
| protein kinase superfamily |

Cdc25C-associated protein kinase 1; cTAK1; C-TAK1; CTAK1ELKL motif kinase 2; EC 2.7.11; EC 2.7.11.1; EMK2; EMK-2; KP78; MAP/microtubule affinity-regulating kinase 3; PAR1A; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78
Mass (kDA):
84.429 kDA

| Human | |
|---|---|
| Location: | 14q32.32-q32.33 |
| Sequence: | 14; NC_000014.9 (103385364..103503831) |
Ubiquitous.
Cell membrane; Peripheral membrane protein. Cell projection, dendrite. Cytoplasm.






PMID: 9543386 by Peng C.Y., et al. C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding.
PMID: 11433294 by Sun T.-Q., et al. PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling.