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- Table of Contents
MARK3 Antibodies
AND MARK3 ELISA kits, MARK3 Proteins
Many biological assays use antibodies to detect MARK3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MARK3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MARK3 antibodies...
Designing an IHC experiment for MARK3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MARK3 IHC GuideMARK3 Infographic by Boster Bio
All MARK3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M05355-1
100 μl/vial
Cat # M05355-1
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A05355-2
100 µg/vial
Cat # A05355-2
100 µg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1698
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1698
1 kit, containing one 96-well plate and all necessary reagents
MARK3 Overview
Facts about MAP/microtubule affinity-regulating kinase 3.
MAP/microtubule affinity-regulating kinase 3 (MARK3)
Serine/threonine-protein kinase (PubMed:23666762). Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4.
Phosphorylates the microtubule- associated protein MAPT/TAU (PubMed:23666762). Phosphorylates CDC25C on 'Ser-216'.
Gene Information
| Human | |
|---|---|
| Gene Name: | MARK3 |
| Uniprot: | P27448 |
| Entrez: | 4140 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
Cdc25C-associated protein kinase 1; cTAK1; C-TAK1; CTAK1ELKL motif kinase 2; EC 2.7.11; EC 2.7.11.1; EMK2; EMK-2; KP78; MAP/microtubule affinity-regulating kinase 3; PAR1A; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78
Molecular Weight
Mass (kDA):
84.429 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q32.32-q32.33 |
| Sequence: | 14; NC_000014.9 (103385364..103503831) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cell membrane; Peripheral membrane protein. Cell projection, dendrite. Cytoplasm.
Diseases
- Neoplasms
- Obesity
- Brain Ischemia
- Infectious Mononucleosis
- Carcinogenesis
- Insulin Resistance
- Fracture
- Malignant Neoplasms
- Mammary Neoplasms
- Osteoporosis
- Cerebral Ischemia
Interacting Proteins
- ASB13
- Ppm1l
- SFN
- TCEA2
- YWHAB
- YWHAG
- YWHAH
- YWHAZ
Pathways
- Cell Cycle
- Mitosis
- Localization
- Dna Damage Checkpoint
- Cell Growth
- Interphase
- Secretion
- Osteoclast Differentiation
- Cell Cycle Checkpoint
- Insulin Secretion
- Hypersensitivity
- Gluconeogenesis
PTMs
- Phosphorylation
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MARK3
bosterbio.com/bosterbio-gene-info-cards/MARK3
References
PMID: 9543386 by Peng C.Y., et al. C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding.
PMID: 11433294 by Sun T.-Q., et al. PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling.