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- Table of Contents
Facts about MARVEL domain-containing protein 1.
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Human | |
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Gene Name: | MARVELD1 |
Uniprot: | Q9BSK0 |
Entrez: | 83742 |
Belongs to: |
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No superfamily |
MARVEL domain-containing protein 1
Mass (kDA):
18.914 kDA
Human | |
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Location: | 10q24.2 |
Sequence: | 10; NC_000010.11 (97713730..97718150) |
Widely expressed in normal tissues. Down- regulated in multiple primary tumors.
Cell membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Nucleus. Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization (By similarity).
PMID: 19364627 by Wang S., et al. Identification and characterization of MARVELD1, a novel nuclear protein that is down-regulated in multiple cancers and silenced by DNA methylation.