ME2 Antibodies

AND ME2 ELISA kits, ME2 Proteins

Many biological assays use antibodies to detect ME2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ME2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ME2 antibodies...

We validate the specificity of these antibodies to ME2 by testing them on tissues known to express ME2 positively and negatively. Browse below to find the ME2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ME2 Infographic by Boster Bio

All ME2 Products

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Product

Figures

Specificity

Applications

Price

Anti-ME2 Antibody Picoband®

Western blot analysis of ME2 using anti-ME2 antibody (A01380-1)

IHC analysis of ME2 using anti-ME2 antibody (A01380-1)

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01380-1
100 μg/vial

Anti-ME2 Antibody

Western blot analysis of ME2 in human spleen tissue lysate with ME2 antibody at (A) 1 and (B) 2μg/ml

Human

ELISA, IF, IHC-P, WB

$481
Cat # A01380
0.1 mg

Anti-ME2 Antibody

Western blot analysis of extracts of various cell lines, using ME2 antibody at 1:1000 dilution

Human, Mouse

IP, WB

$405
Cat # A01380-2
100ul

Anti-ME2 Antibody (C-term)

M01380 staining ME2 in human kidney tissue sections by Immunohistochemistry (IHC-P -paraformaldehyde-fixed, paraffin-embedded sections)

Human, Mouse

IHC-P, WB

$299
Cat # M01380
50 µl

ME2 (NM_002396) Human Over-expression Lysate

Human

$960
Cat # LS004200
20 µg, 100 µg

ME2 Overview

Facts about NAD-dependent malic enzyme, mitochondrial.

ME2 3D structure. Source: alphafold

NAD-dependent malic enzyme, mitochondrial (ME2)

Gene Information

Human
Gene Name:	ME2
Uniprot:	P23368
Entrez:	4200

Family

Belongs to:

malic enzymes family

Alternative Names

EC 1.1.1; EC 1.1.1.38; malate dehydrogenase; Malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase

Molecular Weight

Mass (kDA):
65.444 kDA

Genomic Context


Human

Location:	18q21.2
Sequence:	18; NC_000018.10 (50878702..50954257)

Subcellular Localizations

Mitochondrion matrix.

Diseases

Neoplasms
Epilepsy, Generalized
Epilepsy
Leukemia
Dental Plaque
Malignant Neoplasms
Dysequilibrium Syndrome
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Absence Epilepsy
Convulsion Neonatal
Convulsions

Carcinoma
Febrile Convulsions
Epilepsies, Myoclonic
Idiopathic Generalized Epilepsy
Nervousness
Myoclonic Epilepsy, Juvenile
Familial Benign Neonatal Epilepsy

Pathways

Mating
Conjugation
Secretion
Insulin Secretion
Methylation
Coagulation
Excretion
Transport
Transposition
C4 Photosynthesis
Photosynthesis
Fertilization
Brain Development

Aging
Proteolysis
Oxidative Demethylation
Neurogenesis
Virulence
Reflex
Malate-aspartate Shuttle

PTMs

Oxidation
Reduction
Cleavage
Carboxylation

Methylation
Demethylation
Hydroxylation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ME2

References

PMID: 1993674 by Loeber G., et al. Human NAD(+)-dependent mitochondrial malic enzyme. cDNA cloning, primary structure, and expression in Escherichia coli.

PMID: 11401430 by Yanaihara N., et al. Physical and transcriptional map of a 311-kb segment of chromosome 18q21, a candidate lung tumor suppressor locus.