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Meiob Antibodies
AND Meiob ELISA kits, Meiob Proteins
Many biological assays use antibodies to detect Meiob, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Meiob in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Meiob antibodies...
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Meiob Infographic by Boster Bio
All Meiob Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A13211-2
100 μg/vial
Cat # A13211-2
100 μg/vial
Meiob Overview
Facts about Meiosis-specific with OB domain-containing protein.
Meiosis-specific with OB domain-containing protein (Meiob)
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) fix and crossover formation and promotion of loyal and complete synapsis.
Not required for the initial loading of recombinases but needed to keep a correct number of RAD51 and DMC1 foci following the zygotene stage. May act by ensuring that the insertion of recombinases, which is needed for successful homology search and meiotic recombination.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Meiob |
| Uniprot: | Q9D513 |
| Entrez: | 75178 |
Family
| Belongs to: |
|---|
| MEIOB family |
Alternative Names
C16orf73; chromosome 16 open reading frame 73; gs129; meiosis specific with OB domains
Molecular Weight
Mass (kDA):
52.975 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 17|17 A3.3 |
| Sequence: | 17; |
Tissue Specificity
Sprecifically expressed in early meiotic germ cells: in adult and fetal tissues, detected in fetal ovary, postnatal testis and liver. In the ovary, expression starts at 12.5 dpc, reaches a maximum at 15.5 dpc and decreases to become undetectable in post natal life. In testis, expression starts at 10 days post partum (dpp), reaches a maximum at 20 dpp and is maintained throughout adult life.
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Meiob
bosterbio.com/bosterbio-gene-info-cards/Meiob
References
PMID: 20339383 by Kogo H., et al. Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans.
PMID: 24240703 by Luo M., et al. MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination.