MFF Antibodies

AND MFF ELISA kits, MFF Proteins

Many biological assays use antibodies to detect MFF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MFF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MFF antibodies...

We validate the specificity of these antibodies to MFF by testing them on tissues known to express MFF positively and negatively. Browse below to find the MFF antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for MFF? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MFF Western Blot Guide

Designing an IHC experiment for MFF? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MFF IHC Guide

MFF Infographic by Boster Bio

All MFF Products

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Product

Figures

Specificity

Applications

Price

Anti-MFF Antibody Picoband®

Western blot analysis of MFF using anti-MFF antibody (A02563-1)

IHC analysis of MFF using anti-MFF antibody (A02563-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02563-1
100 μg/vial

MFF (NM_020194) Human Over-expression Lysate

Human

$628
Cat # LS056947
20 µg, 100 µg

MFF Overview

Facts about Mitochondrial fission factor.

MFF 3D structure. Source: alphafold

Mitochondrial fission factor (MFF)

Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. .

Gene Information

Human
Gene Name:	MFF
Uniprot:	Q9GZY8
Entrez:	56947

Family

Belongs to:

Tango11 family

Alternative Names

mitochondrial fission factor

Molecular Weight

Mass (kDA):
38.465 kDA

Genomic Context


Human

Location:	2q36.3
Sequence:	2; NC_000002.12 (227325233..227357836)

Tissue Specificity

Highly expressed in heart, kidney, liver, brain, muscle, and stomach.

Subcellular Localizations

Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.

Diseases

Anxiety Disorders
Neoplasms
Fracture
Glioma
Learning Disorders
Malignant Neoplasms
Stress, Psychological
Mental Disorders
Infective Disorder
Neuroblastoma
Pain
Metal Fever

Cardiac Fibrillation
Cardiac Arrhythmia
Mood Disorders
Attention Deficit Hyperactivity Disorder
Antisocial Personality Disorder
Ventricular Fibrillation
Flushing

Interacting Proteins

FATE1

Pathways

Mitochondrial Fission
Macrophage Fusion
Mitochondrial Fusion
Secretion
Transport
Keratinization
Short-term Memory
Autophagy
Programmed Cell Death
Inhibin Secretion
Fertilization
Immune Response
Sex Determination

Oxidative Phosphorylation
Platelet Aggregation
Embryo Development
Eclosion
Cell Cycle
Organelle Fusion
Membrane Fission

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MFF

References

PMID: 18353969 by Gandre-Babbe S., et al. The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.

PMID: 23921378 by Palmer C.S., et al. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.