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Matrix Gla protein Antibodies

AND MGP ELISA kits, Matrix Gla protein Proteins

Many biological assays use antibodies to detect Matrix Gla protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Matrix Gla protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Matrix Gla protein antibodies...

We validate the specificity of these antibodies to Matrix Gla protein by testing them on tissues known to express MGP positively and negatively. Browse below to find the MGP antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MGP Infographic by Boster Bio

MGP protein infographic

All MGP Products

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Specificity

Applications

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Anti-MGP Antibody Picoband®

1 Citations 6 Q&As

Western blot analysis of MGP using anti-MGP antibody (PB9954)

Western blot analysis of MGP using anti-MGP antibody (PB9954)

IHC analysis of MGP using anti-MGP antibody (PB9954)

Human

IHC, WB

$370
Cat # PB9954
100 μg/vial

Anti-Matrix Gla protein MGP Antibody

Western blot (WB) analysis of MGP pAb at 1:500 dilution
Lane1:CT26 whole cell lysate(20ug)
Lane2:H9C2 whole cell lysate(40ug)
Lane3:Hela whole cell lysate(40ug)
Lane4:MCF-7 whole cell lysate(40ug)
Lane5:PC3 whole cell lysate(40ug)

Western blot (WB) analysis of MGP pAb at 1:500 dilution
Lane1:CT26 whole cell lysate(20ug)
Lane2:H9C2 whole cell lysate(40ug)
Lane3:Hela whole cell lysate(40ug)
Lane4:MCF-7 whole cell lysate(40ug)
Lane5:PC3 whole cell lysate(40ug)

Immunohistochemistry of paraffin-embedded human breast cancer using MGP Rabbit pAb at dilution of 1:100

Immunohistochemistry of paraffin-embedded rat breast using MGP Rabbit pAb at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A01702
100ul

Human MGP Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTP08493
Starting from 20ug

Anti-MGP Mouse Monoclonal Antibody [Clone ID: OTI11G6]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MGP (Right lane) cDNA for 48 hrs and lysed

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MGP (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-MGP mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-MGP mouse monoclonal antibody

Human

IHC, WB

$523
Cat # M01702
100 µl

MGP (NM_000900) Human Over-expression Lysate

MGP Human Over-expression Lysates NM_000900

MGP Human Over-expression Lysates NM_000900

Human

$628
Cat # LS004256
20 µg, 100 µg

MGP Overview

Facts about Matrix Gla protein.

MGP 3D structure

MGP 3D structure. Source: alphafold

Matrix Gla protein (MGP)

Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.

.

Gene Information

Human
Gene Name:	MGP
Uniprot:	P08493
Entrez:	4256

Gene Information

Family

Belongs to:

osteocalcin/matrix Gla protein family

Family

Alternative Names

Cell growth-inhibiting gene 36 protein; matrix Gla protein; MGLAP; NTI

Molecular Weight

Mass (kDA):
12.353 kDA

Molecular Weight

Genomic Context


Human

Location:	12p12.3
Sequence:	12; NC_000012.12 (14880864..14885854, complement)

Subcellular Localizations

Secreted.

Subcellular Localization

Diseases

Calcinosis
Vascular Calcification
Atherosclerosis
Vascular Diseases
Cardiovascular Diseases
Kidney Diseases
Kidney Failure, Chronic
Malignant Neoplasms
Arteriosclerosis
Neoplasms
Hypertrophy
Inflammation

Diabetes Mellitus
Chronic Kidney Disease
Fracture
Vitamin K Deficiency
Osteoporosis
Mucinous Adenocarcinoma

Disease

Pathways

Secretion
Pathogenesis
Localization
Coagulation
Transport
Ossification
Bone Mineralization
Aging
Cell Differentiation
Cell Proliferation
Angiogenesis
Endochondral Ossification
Bone Remodeling

Cell Growth
Bone Resorption
Chondrocyte Differentiation
Reverse Transcription
Cell Adhesion
Cell Death
Osteoblast Differentiation

Pathways

PTMs

Carboxylation
Gamma-carboxylation
Phosphorylation
Cleavage
Decarboxylation
Methylation
Oxidation

Dephosphorylation
Acylation
Deamidation
Biotinylation
Reduction
Glycosylation
Deglycosylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MGP

References

PMID: 2394711 by Cancela M.L., et al. Molecular structure, chromosome assignment, and promoter organization of the human matrix Gla protein gene.

PMID: 3387234 by Kiefer M.C., et al. The cDNA and derived amino acid sequences for human and bovine matrix Gla protein.