Matrix Gla protein Antibodies

AND MGP ELISA kits, Matrix Gla protein Proteins

Many biological assays use antibodies to detect Matrix Gla protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Matrix Gla protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Matrix Gla protein antibodies...

We validate the specificity of these antibodies to Matrix Gla protein by testing them on tissues known to express MGP positively and negatively. Browse below to find the MGP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Matrix Gla protein? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MGP Western Blot Guide

Designing an IHC experiment for Matrix Gla protein? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MGP IHC Guide

MGP Infographic by Boster Bio

All MGP Products

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Product

Figures

Specificity

Applications

Price

Anti-MGP Antibody Picoband®

1 Citations

Western blot analysis of MGP using anti-MGP antibody (PB9954)

IHC analysis of MGP using anti-MGP antibody (PB9954)

Human

IHC, WB

$370
Cat # PB9954
100 μg/vial

MGP (NM_000900) Human Over-expression Lysate

Human

$628
Cat # LS004256
20 µg, 100 µg

Human MGP Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTP08493
Starting from 20ug

MGP Overview

Facts about Matrix Gla protein.

MGP 3D structure. Source: alphafold

Matrix Gla protein (MGP)

Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.

Gene Information

Human
Gene Name:	MGP
Uniprot:	P08493
Entrez:	4256

Family

Belongs to:

osteocalcin/matrix Gla protein family

Alternative Names

Cell growth-inhibiting gene 36 protein; matrix Gla protein; MGLAP; NTI

Molecular Weight

Mass (kDA):
12.353 kDA

Genomic Context


Human

Location:	12p12.3
Sequence:	12; NC_000012.12 (14880864..14885854, complement)

Subcellular Localizations

Secreted.

Diseases

Calcinosis
Vascular Calcification
Atherosclerosis
Vascular Diseases
Cardiovascular Diseases
Kidney Diseases
Kidney Failure, Chronic
Malignant Neoplasms
Arteriosclerosis
Neoplasms
Hypertrophy
Inflammation

Diabetes Mellitus
Chronic Kidney Disease
Fracture
Vitamin K Deficiency
Osteoporosis
Mucinous Adenocarcinoma

Pathways

Secretion
Pathogenesis
Localization
Coagulation
Transport
Ossification
Bone Mineralization
Aging
Cell Differentiation
Cell Proliferation
Angiogenesis
Endochondral Ossification
Bone Remodeling

Cell Growth
Bone Resorption
Chondrocyte Differentiation
Reverse Transcription
Cell Adhesion
Cell Death
Osteoblast Differentiation

PTMs

Carboxylation
Gamma-carboxylation
Phosphorylation
Cleavage
Decarboxylation
Methylation
Oxidation

Dephosphorylation
Acylation
Deamidation
Biotinylation
Reduction
Glycosylation
Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MGP

References

PMID: 2394711 by Cancela M.L., et al. Molecular structure, chromosome assignment, and promoter organization of the human matrix Gla protein gene.

PMID: 3387234 by Kiefer M.C., et al. The cDNA and derived amino acid sequences for human and bovine matrix Gla protein.