MIA2 Antibodies

AND MIA2 ELISA kits, MIA2 Proteins

Many biological assays use antibodies to detect MIA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MIA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MIA2 antibodies...

We validate the specificity of these antibodies to MIA2 by testing them on tissues known to express MIA2 positively and negatively. Browse below to find the MIA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for MIA2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MIA2 IHC Guide

MIA2 Infographic by Boster Bio

All MIA2 Products

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Applications

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Anti-MIA2 Antibody

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung

Western Blot analysis of HEPG2 cells using MIA2 Polyclonal Antibody diluted at 1:500

Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:200

Human, Mouse

IHC, WB

$399
Cat # A08319
100μl

CTAGE5 (MIA2) (NM_203354) Human Over-expression Lysate

Human

$960
Cat # LS004253
20 µg, 100 µg

MIA2 Overview

Facts about Melanoma inhibitory activity protein 2.

Melanoma inhibitory activity protein 2 (MIA2)

Plays a role in the transport of cargos which are too big to fit into COPII-coated vesicles and need certain mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites.

Gene Information

Human
Gene Name:	MIA2
Uniprot:	O15320
Entrez:	4253

Family

Belongs to:

MIA/OTOR family

Alternative Names

FLJ22404; melanoma inhibitory activity 2; melanoma inhibitory activity protein 2

Molecular Weight

Mass (kDA):
159.836 kDA

Genomic Context


Human

Location:	14q21.1
Sequence:	14; NC_000014.9 (39233915..39388522)

Tissue Specificity

Isoform 5A is expressed only in testis (at the protein level). Other isoforms are expressed in several other normal tissues, including brain, muscle and cranial skin. Isoform 5A (at protein level) and isoform 5B are expressed in cutaneous T- cell lymphoma (CTCL) cell lines, colorectal carcinomas, breast carcinomas and melanoma. Isoform 5B, but not isoform 5A, is expressed in head and neck squamous cell carcinoma.

Diseases

Melanoma
Hepatitis, Chronic
Liver Carcinoma
Hepatitis
Carcinoma
Liver Neoplasms
Hepatitis C, Chronic
Hepatitis C
Fibrosis
Neoplasms
Cell Invasion
Liver Diseases

Hepatitis B
Liver Damage
Hepatitis B, Chronic
Malignant Neoplasms
Inflammation
Hepatic Fibrosis
Liver Cirrhosis

Pathways

Cell Proliferation
Cell Growth
Invasive Growth
Pathogenesis

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MIA2

References

PMID: 9356211 by Heckel D., et al. cDNA cloning and chromosomal mapping of a predicted coiled-coil proline- rich protein immunogenic in meningioma patients.

PMID: 12839582 by Usener D., et al. cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor- specific splicing.