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- Table of Contents
MOG Antibodies
AND MOG ELISA kits, MOG Proteins
Many biological assays use antibodies to detect MOG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MOG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MOG antibodies...
Designing a Western blot for MOG? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MOG Western Blot GuideMOG Infographic by Boster Bio
All MOG Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A10993-2
100 µg/vial
Cat # A10993-2
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A03294
100 μg/vial
Cat # A03294
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M03294
100 μl
Cat # M03294
100 μl
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00755
100 μg
Cat # M00755
100 μg
Human
$628
Cat # LS004340
20 µg, 100 µg
Cat # LS004340
20 µg, 100 µg
MOG Overview
Facts about Myelin-oligodendrocyte glycoprotein.
Myelin-oligodendrocyte glycoprotein (MOG)
Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath.
May be involved in completion and/or maintenance of the myelin sheath and in cell- cell communication. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MOG |
| Uniprot: | Q16653 |
| Entrez: | 4340 |
Family
| Belongs to: |
|---|
| immunoglobulin superfamily |
Alternative Names
MGC26137; MOG Ig-AluB; MOG; MOGIG2; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein
Molecular Weight
Mass (kDA):
28.193 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p22.1 |
| Sequence: | 6; NC_000006.12 (29657092..29672365) |
Tissue Specificity
Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.
Subcellular Localizations
[Isoform 1]: Cell membrane; Multi-pass membrane protein.; [Isoform 5]: Cell membrane; Multi-pass membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.; [Isoform 6]: Cell membrane; Single-pass type I membrane protein.; [Isoform 7]: Cell membrane; Single-pass type I membrane protein.; [Isoform 8]: Cell membrane; Single-pass type I membrane protein.; [Isoform 9]: Cell membrane; Single-pass type I membrane protein.
Diseases
- Experimental Autoimmune Encephalomyelitis
- Autoimmune Reaction
- Encephalomyelitis
- Multiple Sclerosis
- Sclerosis
- Nervousness
- Demyelination
- Inflammation
- Autoimmune Diseases
- Demyelinating Diseases
- Autoimmunity
- Cns Disorder
- Multiple Sclerosis, Relapsing-remitting
Pathways
- Pathogenesis
- Immune Response
- Secretion
- Cytokine Production
- Cell Proliferation
- Myelination
- Regeneration
- Cell Activation
- Localization
- T Cell Proliferation
- T Cell Activation
- Inflammatory Response
- Cell Death
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
- Oxidation
- Nitration
- Dephosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MOG
bosterbio.com/bosterbio-gene-info-cards/MOG
References
PMID: 7790876 by Hilton A.A., et al. Characterization of cDNA and genomic clones encoding human myelin oligodendrocyte glycoprotein.
PMID: 7964757 by Pham-Dinh D., et al. Characterization and expression of the cDNA coding for the human myelin/oligodendrocyte glycoprotein.