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- Table of Contents
MPI Antibodies
AND MPI ELISA kits, MPI Proteins
Many biological assays use antibodies to detect MPI, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MPI in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MPI antibodies...
Designing a Western blot for MPI? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MPI Western Blot GuideDesigning an IHC experiment for MPI? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MPI IHC GuideMPI Infographic by Boster Bio
All MPI Products
Product
Figures
Specificity
Applications
Price
Human CCL23/MPIF-1 ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK1224
96 wells/kit, with removable strips.
Cat # EK1224
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK1224
96 wells/kit, with removable strips.
Cat # FEK1224
96 wells/kit, with removable strips.
Anti-MPI Antibody Picoband® (monoclonal, 11I4)
1 Citations
Human
IF, ICC, WB
$370
Cat # M00175
100 μg/vial
Cat # M00175
100 μg/vial
Human, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00175-2
100 μg/vial
Cat # M00175-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A00175
100 μg/vial
Cat # A00175
100 μg/vial
Human
$628
Cat # LS004351
20 µg, 100 µg
Cat # LS004351
20 µg, 100 µg
MPI Overview
Facts about Mannose-6-phosphate isomerase.
Mannose-6-phosphate isomerase (MPI)
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose necessary for a number of critical mannosyl transfer reactions. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MPI |
| Uniprot: | P34949 |
| Entrez: | 4351 |
Family
| Belongs to: |
|---|
| mannose-6-phosphate isomerase type 1 family |
Alternative Names
CDG1B; EC 5.3.1; EC 5.3.1.8; FLJ39201; mannose phosphate isomerase; mannose-6- phosphate isomerase; mannose-6-phosphate isomerase; Phosphohexomutase; phosphomannose isomerase 1; Phosphomannose isomerase; PMI; PMI1phosphohexomutase
Molecular Weight
Mass (kDA):
46.656 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q24.1 |
| Sequence: | 15; NC_000015.10 (74890042..74902219) |
Tissue Specificity
Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
Subcellular Localizations
Cytoplasm.
Diseases
- Coronary Artery Disease
- Infarction
- Myocardial Infarction
- Pain
- Ischemia
- Myocardial Ischemia
- Ventricular Dysfunction, Left
- Stenosis
- Heart Failure
- Heart Diseases
- Coronary Heart Disease
- Chest Pain
- Diabetes Mellitus
Pathways
- Localization
- Glycosylation
- Glomerular Filtration
- Aging
- Pathogenesis
- Translation
- Vasodilation
- Secretion
- Segmentation
- Mating
- Angiogenesis
- Excretion
- Inflammatory Response
PTMs
- Glycosylation
- Phosphorylation
- Cleavage
- Oxidation
- Iodination
- Nitration
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MPI
bosterbio.com/bosterbio-gene-info-cards/MPI
References
PMID: 8307007 by Proudfoot A.E.I., et al. Purification, cDNA cloning and heterologous expression of human phosphomannose isomerase.
PMID: 10980531 by Schollen E., et al. Genomic organization of the human phosphomannose isomerase (MPI) gene and mutation analysis in patients with congenital disorders of glycosylation type Ib (CDG-Ib).