Myoregulin (Mrln)

Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by diminishing the apparent affinity of the ATPase for Ca(2+), thereby acting as a key regulator of skeletal muscle activity. Its high expression in adult skeletal muscle, suggests that it constitutes the predominant regulator of ATP2A1/SERCA1 in adult skeletal muscle.

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