Musculin Antibodies

AND MSC ELISA kits, Musculin Proteins

Many biological assays use antibodies to detect Musculin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Musculin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Musculin antibodies...

We validate the specificity of these antibodies to Musculin by testing them on tissues known to express MSC positively and negatively. Browse below to find the MSC antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MSC Infographic by Boster Bio

All MSC Products

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Product

Figures

Specificity

Applications

Price

Musculin Colorimetric Cell-Based ELISA

Western blot analysis of extracts from Jurkat cells

Human, Mouse

ELISA

$480
Cat # EKC1642
1 kit, containing one 96-well plate and all necessary reagents

Anti-Musculin (R167) MSC Antibody

Immunohistochemistry (IHC) analyzes of Musculin (R167) pAb in paraffin-embedded human lymph node tissue

Human, Mouse, Rat

IHC

$405
Cat # A09472
100ul

MSC (NM_005098) Human Over-expression Lysate

Human

$628
Cat # LS009242
20 µg, 100 µg

MSC Overview

Facts about Musculin.

MSC 3D structure. Source: alphafold

Musculin (MSC)

Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.

Gene Information

Human
Gene Name:	MSC
Uniprot:	O60682
Entrez:	9242

Family

Belongs to:

No superfamily

Alternative Names

ABF1; ABF-1activated B-cell factor 1, homolog of mouse musculin; Activated B-cell factor 1; BHLHA22; bHLHa22activated B-cell factor-1; Class A basic helix-loop-helix protein 22; musculin (activated B-cell factor-1); musculin; MYOR

Molecular Weight

Mass (kDA):
22.068 kDA

Genomic Context


Human

Location:	8q13.3
Sequence:	8; NC_000008.11 (71841542..71844496, complement)

Tissue Specificity

Expressed in lymphoid tissues, B-cell lines and activated B-cells.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Infarction
Malignant Neoplasms
Myocardial Infarction
Tissue Adhesions
Inflammation
Graft-vs-host Disease
Tumor Angiogenesis
Ischemia
Hypoxia
Decreased Immunologic Activity [pe]
Pathologic Neovascularization

Fibrosis
Autoimmune Reaction
Fracture
Malignant Paraganglionic Neoplasm
Diabetes Mellitus
Leukemia

Pathways

Regeneration
Cell Proliferation
Secretion
Angiogenesis
Tissue Regeneration
Cell Differentiation
Cell Cycle
Aging
Cell Adhesion
Cell Growth
Senescence
Cell Migration
Cell Death

Immune Response
Wound Healing
Localization
Stem Cell Differentiation
Osteoblast Differentiation
Pathogenesis
Transdifferentiation

PTMs

Phosphorylation
Methylation
Cleavage
Acetylation
Reduction
Demethylation
Biotinylation
Deacetylation
Oxidation
Ubiquitination

Farnesylation
Glycosylation
Hydroxylation
Dephosphorylation
Prenylation
Acylation
Nitration
Amination
Geranylgeranylation
Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MSC

References

PMID: 9584154 by Massari M.E., et al. Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes.

PMID: 9767165 by Robb L., et al. Musculin: a murine basic helix-loop-helix transcription factor gene expressed in embryonic skeletal muscle.