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- Table of Contents
MSI1 Antibodies
AND MSI1 ELISA kits, MSI1 Proteins
Many biological assays use antibodies to detect MSI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MSI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MSI1 antibodies...
Designing a Western blot for MSI1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MSI1 Western Blot GuideDesigning an IHC experiment for MSI1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MSI1 IHC GuideMSI1 Infographic by Boster Bio
All MSI1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # A05052-1
100 μg/vial
Cat # A05052-1
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M05052-1
100 μg/vial
Cat # M05052-1
100 μg/vial
Human, Mouse
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M05052
100 μl
Cat # M05052
100 μl
Human
ELISA, Flow Cytometry, WB
$370
Cat # A05052-2
100 μg/vial
Cat # A05052-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A05053-2
100 μg/vial
Cat # A05053-2
100 μg/vial
MSI1 Overview
Facts about RNA-binding protein Musashi homolog 1.
RNA-binding protein Musashi homolog 1 (MSI1)
RNA binding protein that regulates the expression of target mRNAs in the translation level. Regulates expression of this NOTCH1 antagonist NUMB.
Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' along with other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | MSI1 |
| Uniprot: | O43347 |
| Entrez: | 4440 |
Family
| Belongs to: |
|---|
| Musashi family |
Alternative Names
MSI1; Musashi (Drosophila) homolog 1; musashi homolog 1 (Drosophila); Musashi1; Musashi-1; RNA-binding protein Musashi homolog 1
Molecular Weight
Mass (kDA):
39.125 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.31 |
| Sequence: | 12; NC_000012.12 (120339662..120369174, complement) |
Tissue Specificity
Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Nervousness
- Brain Neoplasms
- Cell Transformation, Neoplastic
- Glioma
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Glioblastoma
- Medulloblastoma
- Retinoblastoma
- Neoplasm Metastasis
- Adenocarcinoma
Pathways
- Cell Proliferation
- Chromatin Assembly
- Neurogenesis
- Cell Differentiation
- Translation
- Cell Cycle
- Localization
- Fertilization
- Cell Division
- System Development
- Methylation
- Nervous System Development
- Stem Cell Maintenance
PTMs
- Methylation
- Phosphorylation
- Acetylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MSI1
bosterbio.com/bosterbio-gene-info-cards/MSI1
References
PMID: 9790759 by Good P., et al. The human Musashi homolog 1 (MSI1) gene encoding the homologue of Musashi/Nrp-1, a neural RNA-binding protein putatively expressed in CNS stem cells and neural progenitor cells.
PMID: 12054577 by Shu H.-J., et al. Expression of the Musashi1 gene encoding the RNA-binding protein in human hepatoma cell lines.