MTA3 Antibodies

AND MTA3 ELISA kits, MTA3 Proteins

Many biological assays use antibodies to detect MTA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTA3 antibodies...

We validate the specificity of these antibodies to MTA3 by testing them on tissues known to express MTA3 positively and negatively. Browse below to find the MTA3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for MTA3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MTA3 IHC Guide

MTA3 Infographic by Boster Bio

All MTA3 Products

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Anti-MTA3 Antibody

Immunohistochemistry of paraffin-embedded rat liver using MTA3 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded human liver cancer using MTA3 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded mouse testis using MTA3 antibody at dilution of 1:100

Human, Mouse, Rat

IHC, WB

$405
Cat # A05612
100ul

MTA3 (NM_020744) Human Over-expression Lysate

Human

$628
Cat # LS057504
20 µg, 100 µg

MTA3 Overview

Facts about Metastasis-associated protein MTA3.

MTA3 3D structure. Source: alphafold

Metastasis-associated protein MTA3 (MTA3)

Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent fashion, and so the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.

Gene Information

Human
Gene Name:	MTA3
Uniprot:	Q9BTC8
Entrez:	57504

Family

Belongs to:

No superfamily

Alternative Names

member 3; metastasis associated 1 family, member 3; metastasis-associated protein MTA3

Molecular Weight

Mass (kDA):
67.504 kDA

Genomic Context


Human

Location:	2p21
Sequence:	2; NC_000002.12 (42494569..42802118)

Tissue Specificity

Expressed in germinal centers of lymphoid tissues. No expression in nonepithelial cells.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Neoplasm Metastasis
Mammary Neoplasms
Carcinoma
Cell Transformation, Neoplastic
Lymphoma
Tissue Adhesions
Cell Invasion
B-cell Lymphomas
Neoplasm Invasiveness

Adenocarcinoma
Malignant Paraganglionic Neoplasm
Diffuse Large B-cell Lymphoma
Tumor Angiogenesis
Precancerous Conditions
Tumor Progression
Endometrial Neoplasms

Interacting Proteins

EHMT2
GATA3

Pathways

Chromatin Remodeling
Cell Adhesion
Localization
Cell Proliferation
Cell Cycle
Invasive Growth
Cell Development
Epithelial To Mesenchymal Transition
Angiogenesis
Rna Interference
Cell Migration
Atp-dependent Chromatin Remodeling
Mammary Gland Morphogenesis

Aging
Cell Fate Determination
M Phase
Epithelial Cell Development
Cell Differentiation
Placenta Development
Receptor Transactivation

PTMs

Deacetylation
Phosphorylation

Acetylation
Methylation

Research Areas

Breast Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTA3

References

PMID: 12705869 by Fujita N., et al. MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer.

PMID: 15454082 by Fujita N., et al. MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation.