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- Table of Contents
MTHFD1 Antibodies
AND MTHFD1 ELISA kits, MTHFD1 Proteins
Many biological assays use antibodies to detect MTHFD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTHFD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTHFD1 antibodies...
Designing a Western blot for MTHFD1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MTHFD1 Western Blot GuideDesigning an IHC experiment for MTHFD1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MTHFD1 IHC GuideMTHFD1 Infographic by Boster Bio
All MTHFD1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02025-1
100 μg/vial
Cat # A02025-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06289-1
100 μg/vial
Cat # A06289-1
100 μg/vial
MTHFD1 Overview
Facts about C-1-tetrahydrofolate synthase, cytoplasmic.
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1)
Gene Information
| Human | |
|---|---|
| Gene Name: | MTHFD1 |
| Uniprot: | P11586 |
| Entrez: | 4522 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
C1-THF synthase; EC 6.3.4.3; methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolatecyclohydrolase, 10-formyltetrahydrofolate synthetase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1; MTHFCC-1-tetrahydrofolate synthase, cytoplasmic; MTHFDcytoplasmic C-1-tetrahydrofolate synthase
Molecular Weight
Mass (kDA):
101.559 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q23.3 |
| Sequence: | 14; NC_000014.9 (64388353..64460025) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm.
Diseases
- 5,10-methylenetetrahydrofolate Reductase Deficiency
- Malignant Neoplasms
- Neoplasms
- Leukemia
- Hyperhomocysteinemia
- L1 Acute Lymphoblastic Leukemia
- Acute Lymphocytic Leukemia
- Carcinoma
- Carcinogenesis
- Congenital Abnormality
- Cleft Palate
- Head And Neck Neoplasms
- Cleft Lip
Pathways
- Methylation
- Dna Methylation
- Neural Tube Closure
- Tube Closure
- Transport
- Pathogenesis
- Transsulfuration
- Transposition
- Dna Hypermethylation
- Brain Development
PTMs
- Methylation
Research Areas
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTHFD1
bosterbio.com/bosterbio-gene-info-cards/MTHFD1
References
PMID: 3053686 by Hum D.W., et al. Primary structure of a human trifunctional enzyme. Isolation of a cDNA encoding methylenetetrahydrofolate dehydrogenase- methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase.
PMID: 9519408 by Allaire M., et al. The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5-A resolution.