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- Table of Contents
MTHFD1L Antibodies
AND MTHFD1L ELISA kits, MTHFD1L Proteins
Many biological assays use antibodies to detect MTHFD1L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTHFD1L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTHFD1L antibodies...
Designing a Western blot for MTHFD1L? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MTHFD1L Western Blot GuideDesigning an IHC experiment for MTHFD1L? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MTHFD1L IHC GuideMTHFD1L Infographic by Boster Bio
All MTHFD1L Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06289-1
100 μg/vial
Cat # A06289-1
100 μg/vial
MTHFD1L Overview
Facts about Monofunctional C1-tetrahydrofolate synthase, mitochondrial.
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L)
May supply the missing metabolic reaction required to connect the mitochondria and the cytoplasm in the mammalian version of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic actions of MTHFD2. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MTHFD1L |
| Uniprot: | Q6UB35 |
| Entrez: | 25902 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
10-formyl-THF synthetase; dJ292B18.2; DKFZp586G1517; EC 6.3.4.3; FLJ21145; formyltetrahydrofolate synthetase domain containing 1; Formyltetrahydrofolate synthetase; FTHFSDC1; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; mitochondrial C1-tetrahydrofolate synthase; mitochondrial C1-tetrahydrofolate synthetase; monofunctional C1-tetrahydrofolate synthase, mitochondrial; MTC1THFS
Molecular Weight
Mass (kDA):
105.79 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q25.1 |
| Sequence: | 6; NC_000006.12 (150865679..151101887) |
Tissue Specificity
Detected in most tissues, highest expression found in placenta, thymus and brain. Low expression is found in liver and skeletal muscle. Up-regulated in colon adenocarcinoma.
Subcellular Localizations
Mitochondrion.
Diseases
- Coronary Artery Disease
- Alzheimer's Disease
- Coronary Heart Disease
- Infarction
- Myocardial Infarction
- Dysequilibrium Syndrome
- Heart Diseases
- Malignant Neoplasms
- Diabetes Mellitus
- Moyamoya Disease
- Stenosis
- Malignant Neoplasm Of Breast
- Dementia
Pathways
- Methylation
- Mrna Splicing
- Cell Proliferation
- Cell Cycle
- Dna Methylation
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTHFD1L
bosterbio.com/bosterbio-gene-info-cards/MTHFD1L
References
PMID: 12937168 by Prasannan P., et al. Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls.
PMID: 15013446 by Sugiura T., et al. A novel mitochondrial C1-tetrahydrofolate synthetase is upregulated in human colon adenocarcinoma.