This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Methionine synthase Antibodies
AND MTR ELISA kits, Methionine synthase Proteins
Many biological assays use antibodies to detect Methionine synthase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Methionine synthase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Methionine synthase antibodies...
Designing a Western blot for Methionine synthase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MTR Western Blot GuideDesigning an IHC experiment for Methionine synthase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MTR IHC GuideMTR Infographic by Boster Bio
All MTR Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01140-2
100 μg/vial
Cat # A01140-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, WB
$370
Cat # A01401-1
100 μg/vial
Cat # A01401-1
100 μg/vial
Human
$628
Cat # LS005442
20 µg, 100 µg
Cat # LS005442
20 µg, 100 µg
MTR Overview
Facts about Methionine synthase.
Methionine synthase (MTR)
Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MTR |
| Uniprot: | Q99707 |
| Entrez: | 4548 |
Family
| Belongs to: |
|---|
| vitamin-B12 dependent methionine synthase family |
Alternative Names
5-methyltetrahydrofolate-homocysteine methyltransferase 1; 5-methyltetrahydrofolate-homocysteine methyltransferase; cblG; cobalamin-dependent methionine synthase; EC 2.1.1.13; FLJ33168; FLJ43216,5-methyltetrahydrofolate--homocysteine methyltransferase; FLJ45386; methionine synthase; MS; Vitamin-B12 dependent methionine synthase
Molecular Weight
Mass (kDA):
140.527 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q43 |
| Sequence: | 1; NC_000001.11 (236794304..236903981) |
Tissue Specificity
Widely expressed. Expressed at the highest levels in pancreas, heart, brain, skeletal muscle and placenta. Expressed at lower levels in lung, liver and kidney.
Subcellular Localizations
Cytoplasm.
Diseases
- 5,10-methylenetetrahydrofolate Reductase Deficiency
- Multiple Sclerosis
- Sclerosis
- Malignant Neoplasms
- Neoplasms
- Demyelination
- Atrophy
- Multiple Sclerosis, Relapsing-remitting
- Tissue Damage
- Multiple Sclerosis, Chronic Progressive
- Edema
- Brain Injuries
- Cognition Disorders
Interacting Proteins
- MMACHC
Pathways
- Transport
- Methylation
- Dna Methylation
- Myelination
- Pathogenesis
- Aging
- Localization
- Segmentation
- Cognition
- Dna Hypomethylation
- Secretion
- Mrna Transport
- Amino Acid Transport
PTMs
- Methylation
- Reduction
- Cleavage
- Oxidation
- Phosphorylation
- Carboxylation
- Phosphorothioation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTR
bosterbio.com/bosterbio-gene-info-cards/MTR
References
PMID: 8968737 by Leclerc D., et al. Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders.
PMID: 8968735 by Li Y.N., et al. Cloning, mapping and RNA analysis of the human methionine synthase gene.