MTUS1 Antibodies

AND MTUS1 ELISA kits, MTUS1 Proteins

Many biological assays use antibodies to detect MTUS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTUS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTUS1 antibodies...

We validate the specificity of these antibodies to MTUS1 by testing them on tissues known to express MTUS1 positively and negatively. Browse below to find the MTUS1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: COG6

MTUS1 Infographic by Boster Bio

All MTUS1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MTUS1 Antibody Picoband®

13 Q&As

IF analysis of MTUS1 using anti-MTUS1 antibody (A04047-1)

Western blot analysis of MTUS1 using anti-MTUS1 antibody (A04047-1)

Human, Mouse, Rat

ELISA, IF, ICC, WB

$370
Cat # A04047-1
100 μg/vial

MTUS1 Overview

Facts about Microtubule-associated tumor suppressor 1.

MTUS1 3D structure. Source: alphafold

Microtubule-associated tumor suppressor 1 (MTUS1)

Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be necessary for AGTR2 cell surface expression.

Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell regeneration, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.

Gene Information

Human
Gene Name:	MTUS1
Uniprot:	Q9ULD2
Entrez:	57509

Family

Belongs to:

MTUS1 family

Alternative Names

Angiotensin-II type 2 receptor-interacting protein; AT2 receptor-binding protein; AT2R binding protein; ATBPATIP1; ATIP; DKFZp586D1519; erythroid differentiation-related; FLJ14295; GK1; KIAA1288DKFZp686F20243; microtubule associated tumor suppressor 1; microtubule-associated tumor suppressor 1; Mitochondrial tumor suppressor 1; mitochondrial tumor suppressor gene 1; MP44; MTSG1AT2 receptor-interacting protein; transcription factor MTSG1

Molecular Weight

Mass (kDA):
141.397 kDA

Genomic Context


Human

Location:	8p22
Sequence:	8; NC_000008.11 (17643794..17801579, complement)

Tissue Specificity

Ubiquitously expressed (at protein level). Highly expressed in brain. Down-regulated in ovarian carcinoma, pancreas carcinoma, colon carcinoma and head and neck squamous cell carcinoma (HNSCC). Isoform 1 is the major isoform in most peripheral tissues. Isoform 2 is abundant in most peripheral tissues. Isoform 3 is the major isoform in brain, female reproductive tissues, thyroid and heart. Within brain it is highly expressed in corpus callosum and pons. Isoform 6 is brain- specific, it is the major isoform in cerebellum and fetal brain.

Subcellular Localizations

Mitochondrion. Golgi apparatus. Cell membrane. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin-II.; [Isoform 1]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Localizes with the mitotic spindle during mitosis and with the intercellular bridge during cytokinesis.